Transplantation

We advance transplantation science through innovative research in organ preservation, immunomodulation, and regeneration. By combining machine perfusion technologies, preclinical models, and novel therapeutic strategies such as senolytics and defatting, we aim to improve graft outcomes and translate discoveries into clinical practice.

Transplantation

We advance transplantation science through innovative research in organ preservation, immunomodulation, and regeneration. By combining machine perfusion technologies, preclinical models, and novel therapeutic strategies such as senolytics and defatting, we aim to improve graft outcomes and translate discoveries into clinical practice.

Regenerative Medicine

Our novel concept of metabolic reprogramming envisions reconstitution of endogenous repair in severely steatotic liver grafts during extracorporeal machine perfusion in the period between explantation and implantation.

Digital Surgery

With Digital Surgery we shape a new concept of surgery that takes into account how digital technologies are changing surgical workflows and decision-making processes from diagnosis and prevention, through knowledge organization and hospital management, to the operating theatre. We identify needs from the field of emerging health technologies and translate them into concepts for digital healthcare. Our current research areas include AI, robotic surgery, and extended reality.

Digital Surgery

With Digital Surgery we shape a new concept of surgery that takes into account how digital technologies are changing surgical workflows and decision-making processes from diagnosis and prevention, through knowledge organization and hospital management, to the operating theatre. We identify needs from the field of emerging health technologies and translate them into concepts for digital healthcare. Our current research areas include AI, robotic surgery, and extended reality.

Oncology

A new approach to overcome organ scarcity by in vitro generation of tissue and organ structures is decellularisation and recellularisation of tissues or whole organs. This concept is based on the idea of composing biologic scaffolds by removing cellular and antigen-presenting components from tissues or organs.

We thank the Deutsche Forschungsgemeinschaft (German Research Fondation, DFG), the Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research, BMBF), the European Region Development Fund (EFRE), the BIH Charité Clinician Scientist program, the Fiebig-Stiftung, the Einstein Center for Regenerative Therapies (ECRT), the Stiftung Charité, the Else Körner Fresenius Stiftung (EKFS), and the Einstein Foundation for their financial support.

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© 2025 Prof. Dr. Igor M. Sauer | Charité - Universitätsmedizin Berlin | Disclaimer

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