Selected Publications
Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the
Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.

2024

Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome
N.N. Roschke, K.H. Hillebrandt, D. Polenz, O. Klein, J.M.G.V. Gassner, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner.

PLOS ONE, 2024 – in press

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Proteomic analysis of decellularized mice liver and kidney extracellular matrices
A.M. Diedrich, A. Daneshgar, P. Tang, O. Klein, A. Mohr, O.A. Onwuegbuchulam, S. von Rueden, K. Menck, A. Bleckmann, M.A. Juratli, F. Becker, I.M. Sauer, K.H. Hillebrandt, A. Pascher, B. Struecker

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Improved outcomes after hypothermic oxygenated machine perfusion in liver transplantation-Long-term follow-up of a multicenter randomized controlled trial.
Z. Czigany, D. Uluk, S. Pavicevic, I. Lurje, J. Froněk, Th. Keller, P. Strnad, D. Jiang, T. Gevers, D. Koliogiannis, M. Guba, R.H. Tolba, F.A. Meister, U.P. Neumann, M. Kocik, M. Kysela, I.M. Sauer, N. Raschzok, W. Schöning, I. Popescu, F. Tacke, J. Pratschke, G. Lurje

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Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels
A. Almalla, L. Elomaa, L. Bechtella, A. Daneshgar, P. Yavvari, Z. Mahfouz, P. Tang, B. Koksch, I. Sauer, K. Pagel, K.H. Hillebrandt, M. Weinhart

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Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering  
M.N. Andreas, A.K. Boehm, P. Tang, S. Moosburner, O. Klein, A. Daneshgar, J.M.G.V. Gaßner, N. Raschzok, D. Wulsten, J.-C. Rückert, S. Spuler, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

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Body composition is associated with disease aetiology and prognosis in patients undergoing resection of intrahepatic cholangiocarcinoma.
I. Lurje, D. Uluk, S. Pavicevic, M.D. Phan, D. Eurich, U. Fehrenbach, D. Geisel, T.A. Auer, U. Pelzer, D.P. Modest, N. Raschzok, I.M. Sauer, W. Schöning, F. Tacke, J. Pratschke, G. Lurje G

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Validation of risk scores for allograft failure after liver transplantation in Germany: a retrospective cohort analysis
S. Moosburner, L. Wiering, N. Roschke, A. Winter, Axel; M. Demir, J.M.G.V. Gaßner, M. Zimmer, P. Ritschl, B. Globke, G. Lurje, F. Tacke, W. Schöning, J. Pratschke, R. Öllinger, I.M. Sauer, N. Raschzok

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Bioactive photocrosslinkable resin solely based on refined decellularized small intestine submucosa for vat photopolymerization of in vitro tissue mimics
L. Elomaa, L. Gerbeth, A. Almalla, N. Fribiczer, A. Daneshgar, P. Tang, K. Hillebrandt, S. Seiffert, I.M. Sauer, B. Siegmund, M. Weinhart

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Augmenting Image-Guided Procedures through In Situ Visualization of 3D Ultrasound via a Head-Mounted Display
F. von Haxthausen, Ch. Rüger, M.M. Sieren, R. Kloeckner, F. Ernst

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2022

Inhibition of Vascular Endothelial Growth Factor Protects against the Development of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome in Wild-Type but Not in CD39-Null Mice
S. Knitter, G. Duwe, A.S. Beierle, S. Pesthy, P.V. Ritschl, K.H. Hillebrandt, A. Arnold, T. Malinka, D.P. Modest, M. Bahra, J. Pratschke, I.M. Sauer, M. Schmelzle, A. Andreou

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Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues
J. Snellings, E. Keshi, P. Tang, A. Daneshgar, E.C. Willma, L. Haderer, O. Klein, F. Krenzien, Th. Malink, P. Asbach, J. Pratschke, I.M. Sauer, J. Braun, I. Sack, K. Hillebrandt

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Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models
V. Muth, J.M.G.V. Gassner, S. Moosburner, G. Lurje, J. Michelotto, F. Strobl, K. Knaub, C. Engelmann, F. Tacke, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok N

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Tissue engineering for the diaphragm and its various therapeutic possibilities – A Systematic Review
A.K. Boehm, K.H. Hillebrandt, T. Dziodzio, F. Krenzien, J. Neudecker, S. Spuler, J. Pratschke, I.M. Sauer, M.N. Andreas

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Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies?
M. Felsenstein, F. Lindhammer, M. Feist, K.H. Hillebrandt, L. Timmermann, C. Benzing, B. Globke, D. Zocholl, M. Hu, U. Fehrenbach, B.V. Sinn, U. Pelzer, I.M. Sauer, J. Pratschke, T. Malinka

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Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing
J.M. Alves, S. Prado-López, L. Tomás, M. Valecha, N. Estévez-Gómez, P. Alvariño, D. Geisel, D.P. Modest, I.M. Sauer, J. Pratschke, N. Raschzok, C. Sers, S. Mamlouk, D. Posada

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Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next-Generation Outcome Prediction in Transplantation Medicine
S. Moosburner, J.M.G.V. Gassner, J. Pratschke, I.M. Sauer, N. Raschzok

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Prognostic and Predictive Molecular Markers in Cholangiocarcinoma
S. Pavicevic, S. Reichelt, D. Uluk, I. Lurje, C. Engelmann, D.P. Modest, U. Pelzer, F. Krenzien, N. Raschzok, C. Benzing, I.M. Sauer, S. Stintzing, F. Tacke, W. Schöning, M. Schmelzle, J. Pratschke, G. Lurje

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FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer
N. Raschzok, S. Stintzing, V. Heinemann, G. Rauch, J. Ricke, M. Guckenberger, A. Kurreck, A.H.S. Alig, A. Stahler, L. Bullinger, M. Schmelzle, W. Schöning, G. Lurje, F. Krenzien, O. Haase, B. Rau, B. Gebauer, I.M. Sauer, J. Pratschke, D.P. Modest DP

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Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
N. Krause, J. Mengwasser, E. Phithak, F. Beato, M. Appis, E.L. Milford, J. Pratschke J, I. Sauer, A. Kuehl, A. Vogel, M. Goodyear, L. Hammerich, F. Tacke, J.F. Haas, T. Müller, N. Utku N

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[Digital documentation of complications in visceral surgery: possibilities and evaluation of an instrument for quality management]
A. Winter, M.M. Maurer, M. Schmelzle, T. Malinka, M. Biebl, P. Fikatas, D. Kröll, I.M. Sauer, M. Hippler-Benscheidt, J, Pratschke, S. Chopra

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Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity
E. Keshi, P. Tang, M. Weinhart, H. Everwien, S. Moosburner, N. Seiffert, M. Lommel, U. Kertzscher, B. Globke, A. Reuztel-Selke, B. Strücker, J. Pratschke, I.M. Sauer, N. Haep, K.H. Hillebrandt

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Cancer Associated Fibroblasts Derived from Pancreatic Adenocarcinoma and Their Role in Cell Migration
E. von Hoerschelmann, C.C.M. Neumann, M. Felsenstein, J. Gogolok, A. Reutzel-Selke, I.M. Sauer, J. Pratschke, M. Bahra, R.B, Schmuck

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Perioperative Risk Assessment in Pancreatic Surgery Using Machine Learning
B. Pfitzner, J. Chromik, R. Brabender, E. Fischer, A. Kromer, A. Winter, S. Moosburner, I.M. Sauer, T. Malinka, J. Pratschke, B. Arnrich, M.M. Maurer

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Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies
S. Gül-Klein, H. Hegermann, R. Röhle, M. Schmelzle, F. Tacke, W. Schöning, R. Öllinger, T. Dziodzio, P. Maier, J.M. Plewe, D. Horst, I.M. Sauer, J. Pratschke, N. Lachmann, D. Eurich

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Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study
K. Kamali, M. Schmelzle, C. Kamali, P. Brunnbauer, K. Splith, A. Leder, N. Berndt, K.H. Hillebrandt, N. Raschzok, L. Feldbrügge, M. Felsenstein, J. Gaßner, P. Ritschl, G. Lurje, W. Schöning, C. Benzing, J. Pratschke, F. Krenzien

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The Human Liver Matrisome – Proteomic Analysis of Native and Fibrotic Human Liver Extracellular Matrices for Organ Engineering Approaches
A. Daneshgar, O. Klein, G. Nebrich, M. Weinhart, P. Tang, A. Arnold, I. Ullah, J. Pohl, S. Moosburner, N. Raschzok, B. Strücker, M. Bahra, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

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Tissue-based miRNA mapping in alcoholic liver cirrhosis: different profiles in cirrhosis with or without hepatocellular carcinoma
P. Felgendreff, N. Raschzok, K. Kunze, A. Leder, S. Lippert, S. Klunk, H.M. Tautenhahn, H.M. Hau, R.B. Schmuck, A. Reutzel-Selke, I.M. Sauer, M. Bartels, M.H. Morgül

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2019

Hepatocyte Transplantation to the Liver via the Splenic Artery in a Juvenile Large Animal Model
J. Siefert, K.H. Hillebrandt, S. Moosburner, P. Podrabsky, D. Geisel, T. Denecke, J.K. Unger, B. Sawitzki, S. Gül-Klein, S. Lippert, P. Tang, A. Reutzel-Selke, M.H. Morgul, A.W. Reske, S. Kafert-Kasting, W. Rüdinger, J. Oetvoes, J. Pratschke, I.M. Sauer, N. Raschzok

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Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner
S. Kuhn, K. Splith, C. Ballschuh, L. Feldbrügge, F. Krenzien, G. Atanasov, C. Benzing, H.M. Hau, C. Engelmann, T. Berg, J. Schulte Am Esch, J. Pratschke, S.C. Robson, M. Schmelzle

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Title - Change Me

Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans
H. Napierala, K. Hillebrandt, N. Haep, P. Tang, M. Tintemann, J. Gassner, M. Noesser, H. Everwien, N. Seiffert, M. Kluge, E. Teegen, D. Polenz, S. Lippert, D. Geisel, A. Reutzel-Selke, N. Raschzok, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker

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Title - Change Me

The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism
C. von Loeffelholz, S. Lieske, F. Neuschäfer-Rube, D.M. Willmes, N. Raschzok , I.M. Sauer, J. König, M. Fromm, P. Horn, A. Chatzigeorgiou, A. Pathe-Neuschäfer-Rube, J. Jordan, A.F. Pfeiffer, C. Mingrone, S.R. Bornstein, P. Stroehle, C. Harms, F.T. Wunderlich, S.L. Helfand , M. Bernier, R. de Cabo, G.I. Shulman, T. Chavakis, G.P. Püschel, A.L. Birkenfeld

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Title - Change Me

Hepatotoxicity following systemic therapy for colorectal liver metastases and the impact of chemotherapy-associated liver injury on outcomes after curative liver resection
G. Duwe, S. Knitter, S. Pesthy, A.S. Beierle, M. Bahra, M. Schmelzle, R.B. Schmuck, P. Lohneis, N. Raschzok, R. Öllinger, M. Sinn, B. Struecker, I.M. Sauer, J. Pratschke, A. Andreou

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Title - Change Me

Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions
B. Struecker, A. Butter, K. Hillebrandt, D. Polenz , A. Reutzel-Selke, P. Tang, S. Lippert, A. Leder, S. Rohn, D. Geisel, T. Denecke, K. Aliyev, K. Jöhrens, N. Raschzok, P. Neuhaus, J. Pratschke, I.M. Sauer

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Title - Change Me

Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver
C. von Loeffelholz, S. Döcke, J.F. Lock, S. Lieske, P. Horn, J. Kriebel, S. Wahl, P. Singmann, T. de Las Heras Gala, H. Grallert, N. Raschzok, I.M. Sauer, R. Heller, G. Jahreis, R.A. Claus, M. Bauer, M. Stockmann, A.L. Birkenfeld, A.F. Pfeiffer

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Title - Change Me

Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue – A statistical model based on stepwise penalized logistic regression
M.H. Morgul, S. Klunk, Z. Anastasiadou, U. Gauger, C. Dietel, A. Reutzel-Selke, P. Felgendref, H.M. Hau, H.M. Tautenhahn, R.B. Schmuck, N. Raschzok, I.M. Sauer, M. Bartels

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Title - Change Me

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
Noll EM, Eisen C, Stenzinger A, Espinet E, Muckenhuber A, Klein C, Vogel V, Klaus B, Nadler W, Rösli C, Lutz C, Kulke M, Engelhardt J, Zickgraf FM, Espinosa O, Schlesner M, Jiang X, Kopp-Schneider A, Neuhaus P, Bahra M, Sinn BV, Eils R, Giese NA, Hackert T, Strobel O, Werner J, Büchler MW, Weichert W, Trumpp A, Sprick MR. 

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Title - Change Me

Perioperative treatment options in resectable pancreatic cancer - how to improve long-term survival
Sinn M, Bahra M, Denecke T, Travis S, Pelzer U, Riess H. 

Gastrointest Oncol. 2016;8(3)
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Title - Change Me

P53 overexpression and Ki67-index are associated with outcome in ductal pancreatic adenocarcinoma with adjuvant gemcitabine treatment
Striefler JK, Sinn M, Pelzer U, Jühling A, Wislocka L, Bahra M, Sinn BV, Denkert C, Dörken B, Oettle H, Riess H, Bläker H, Lohneis P.

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Title - Change Me

Pancreatogastrostomy Versus Pancreatojejunostomy for RECOnstruction After PANCreatoduodenectomy (RECOPANC, DRKS 00000767): Perioperative and Long-term Results of a Multicenter Randomized Controlled Trial
Keck T, Wellner UF, Bahra M, Klein F, Sick O, Niedergethmann M, Wilhelm TJ, Farkas SA, Börner T, Bruns C, Kleespies A, Kleeff J, Mihaljevic AL, Uhl W, Chromik A, Fendrich V, Heeger K, Padberg W, Hecker A, Neumann UP, Junge K, Kalff JC, Glowka TR, Werner J, Knebel P, Piso P, Mayr M, Izbicki J, Vashist Y, Bronsert P, Bruckner T, Limprecht R, Diener MK, Rossion I, Wegener I, Hopt UT.

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Title - Change Me

Human equilibrative nucleoside transporter 1 expression analysed by the clone SP 120 rabbit antibody is not predictive in patients with pancreatic cancer treated with adjuvant gemcitabine - Results from the CONKO-001 trial
Sinn M, Riess H, Sinn BV, Stieler JM, Pelzer U, Striefler JK, Oettle H, Bahra M, Denkert C, Bläker H, Lohneis P.

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Title - Change Me

Ataxia-telangiectasia-mutated protein kinase levels stratify patients with pancreatic adenocarcinoma into prognostic subgroups with loss being a strong indicator of poor survival
Kamphues C, Bova R, Bahra M, Klauschen F, Muckenhuber A, Sinn BV, Warth A, Goeppert B, Endris V, Neuhaus P, Weichert W, Stenzinger A.

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Title - Change Me

Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay
Arnold A, Bahra M, Lenze D, Bradtmöller M, Guse K, Gehlhaar C, Bläker H, Heppner FL, Koch A. 

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Title - Change Me

Implications of imaging criteria for the management and treatment of intraductal papillary mucinous neoplasms - benign versus malignant findings 
Walter TC, Steffen IG, Stelter LH, Maurer MH, Bahra M, Faber W, Klein F, Bläker H, Hamm B, Denecke T, Grieser C.

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Title - Change Me

Patient and tumor biology predict survival beyond the Milan criteria in liver transplantation for hepatocellular carcinoma.
Andreou A, Gül S, Pascher A, Schöning W, Al-Abadi H, Bahra M, Klein F, Denecke T, Strücker B, Puhl G, Neuhaus P, Pratschke J, Seehofer D.

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Title - Change Me

CD44 and CXCL9 serum protein levels predict the risk of clinically significant allograft rejection after liver transplantation
N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, M.H. Morgul, U. Gauger,K.A. Prabowo, L.-M. Tannus, A. Leder, B. Struecker, S. Boas-Knoop, M. Bartels, S. Jonas, Ch. Lojewski, G. Puhl, D. Seehofer, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer

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Title - Change Me

Response to preoperative chemotherapy predicts survival in patients undergoing hepatectomy for liver metastases from gastric and esophageal cancer
Andreou A, Viganò L, Zimmitti G, Seehofer D, Dreyer M, Pascher A, Bahra M, Schoening W, Schmitz V, Thuss-Patience PC, Denecke T, Puhl G, Vauthey JN, Neuhaus P, Capussotti L, Pratschke J, Schmidt SC.

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Title - Change Me

DNA index is a strong predictive marker in intrahepatic cholangiocarcinoma: the results of a five-year prospective study
Kamphues C, Al-Abadi N, Dürr A, Bova R, Klauschen F, Stenzinger A, Bahra M, Al-Abadi H, Neuhaus P, Seehofer D.

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Title - Change Me

Porcine liver decellularization under oscillating pressure conditions – A technical refinement to improve the homogeneity of the decellularization process
B. Struecker, K. Hillebrandt, R. Voitl, A. Butter, R.B. Schmuck, A. Reutzel-Selke, D. Geisel, K. Joehrens, P.A. Pickerodt, N. Raschzok, G. Puhl, P. Neuhaus, J. Pratschke, I.M. Sauer

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Title - Change Me

Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial
Pelzer U, Hilbig A, Stieler JM, Bahra M, Sinn M, Gebauer B, Dörken B, RiessPelzer U, Hilbig A, Stieler JM, Bahra M, Sinn M, Gebauer B, Dörken B, Riess

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Title - Change Me

KRAS mutations in codon 12 or 13 are associated with worse prognosis in pancreatic ductal adenocarcinoma
Sinn BV, Striefler JK, Rudl MA, Lehmann A, Bahra M, Denkert C, Sinn M, Stieler J, Klauschen F, Budczies J, Weichert W, Stenzinger A, Kamphues C, Dietel M, Riess H. 

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Title - Change Me

α-Smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study
Sinn M, Denkert C, Striefler JK, Pelzer U, Stieler JM, Bahra M, Lohneis P, Dörken B, Oettle H, Riess H, Sinn BV.

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Title - Change Me

Prognostic factors for long-term survival in patients with ampullary carcinoma: the results of a 15-year observation period after pancreaticoduodenectomy
Klein F, Jacob D, Bahra M, Pelzer U, Puhl G, Krannich A, Andreou A, Gül S, Guckelberger O.

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Title - Change Me

RAS Mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases
Mise Y, Zimmitti G, Shindoh J, Kopetz S, Loyer EM, Andreou A, Cooper AB, Kaur H, Aloia TA, Maru DM, Vauthey JN.

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Title - Change Me

Residual tumor thickness at the tumor-normal tissue interface predicts the recurrence-free survival in patients with liver metastasis of breast cancer
Zhou JH, Rosen D, Andreou A, Brouquet A, Abbott D, Loyer E, Gonzalez-Angulo AM, Kopetz S, Meric-Bernstam F, Kuerer H, Abdalla E, Vauthey JN, Sahin AA, Maru DM.

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Title - Change Me

Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy
Andreou A, Aloia TA, Brouquet A, Dickson PV, Zimmitti G, Maru DM, Kopetz S, Loyer EM, Curley SA, Abdalla EK, Vauthey JN.

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Title - Change Me

From the International Cooperative Study Group on Hepatocellular Carcinoma. Improved long-term survival after major resection for hepatocellular carcinoma: a multicenter analysis based on a new definition of major hepatectomy
Andreou A, Vauthey JN, Cherqui D, Zimmitti G, Ribero D, Truty MJ, Wei SH, Curley SA, Laurent A, Poon RT, Belghiti J, Nagorney DM, Aloia TA.

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Title - Change Me

Does long-term survival in patients with pancreatic cancer really exist? Results from the CONKO-001 study
Sinn M, Striefler JK, Sinn BV, Sallmon D, Bischoff S, Stieler JM, Pelzer U, Bahra M, Neuhaus P, Dörken B, Denkert C, Riess H, Oettle H.

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Title - Change Me

Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging
Grieser C, Heine G, Stelter L, Steffen IG, Rothe JH, Walter TC, Fischer C, Bahra M, Denecke T.

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Title - Change Me

Long-term results of liver resection for hepatocellular carcinoma in noncirrhotic liver
Faber W, Sharafi S, Stockmann M, Denecke T, Sinn B, Puhl G, Bahra M, Malinowski MB, Neuhaus P, Seehofer D.

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Title - Change Me

RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases
Vauthey JN, Zimmitti G, Kopetz SE, Shindoh J, Chen SS, Andreou A, Curley SA, Aloia TA, Maru DM.

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Title - Change Me

Adjuvant chemotherapy with FOLFOX for primary colorectal cancer is associated with increased somatic gene mutations and inferior survival in patients undergoing hepatectomy for metachronous liver metastases
Andreou A, Kopetz S, Maru DM, Chen SS, Zimmitti G, Brouquet A, Shindoh J, Curley SA, Garrett C, Overman MJ, Aloia TA, Vauthey JN.

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Title - Change Me

Liver resection for liver metastases from nondigestive endocrine cancer: extrahepatic disease burden defines outcome
Andreou A, Brouquet A, Bharathy KGS, Perrier ND, Abdalla EK, Curley SA, Glanemann M, Seehofer D, Neuhaus P, Vauthey JN, Aloia TA.

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Title - Change Me

Liver resection for liver metastases from nondigestive endocrine cancer: extrahepatic disease burden defines outcome
Andreou A, Brouquet A, Bharathy KGS, Perrier ND, Abdalla EK, Curley SA, Glanemann M, Seehofer D, Neuhaus P, Vauthey JN, Aloia TA.

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Title - Change Me

DNA Index as a Strong Prognostic Factor in Patients with Adenocarcinoma of the Pancreatic Head: Results of a 5-Year Prospective Study
Kamphues C, Al-Abadi H, Dürr A, Al-Abadi N, Schricke D, Bova R, Müller V, Stenzinger A, Klauschen F, Seehofer D, Neuhaus P, Bahra M.

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Title - Change Me

Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas
Bahra M, Kamphues C, Boas-Knoop S, Lippert S, Esendik U, Schüller U, Hartmann W, Waha A, Neuhaus P, Heppner F, Pietsch T, Koch A.

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Title - Change Me

Role of IL28B polymorphism in the development of hepatitis C virus-induced hepatocellular carcinoma, graft fibrosis, and posttransplant antiviral therapy
Eurich D, Boas-Knoop S, Bahra M, Neuhaus R, Somasundaram R, Neuhaus P, Neumann U, Seehofer D.

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Title - Change Me

High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer
Klauschen F, von Winterfeld M, Stenzinger A, Sinn BV, Budczies J, Kamphues C, Bahra M, Wittschieber D, Weichert W, Striefler J, Riess H, Dietel M, Denkert C.

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Title - Change Me

Preliminary experience with CT-guided high-dose rate brachytherapy as an alternative treatment for hepatic recurrence of cholangiocarcinoma
Kamphues C, Seehofer D, Collettini F, Bahra M, Neuhaus P, Wust P, Denecke T, Gebauer B, Schnapauff D.

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Title - Change Me

Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes
Winter C, Kristiansen G, Kersting S, Roy J, Aust D, Knösel T, Rümmele P, Jahnke B, Hentrich V, Rückert F, Niedergethmann M, Weichert W, Bahra M, Schlitt HJ, Settmacher U, Friess H, Büchler M, Saeger HD, Schroeder M, Pilarsky C, Grützmann R.

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Title - Change Me

Microvascular invasion does not predict long-term survival in hepatocellular carcinoma up to 2 cm: reappraisal of the staging system for solitary tumors
Shindoh J, Andreou A, Aloia TA, Zimmitti G, Lauwers GY, Laurent A, Nagorney DM, Belghiti J, Cherqui D, Poon RT, Kokudo N, Vauthey JN.

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Title - Change Me

High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome
Brouquet A, Abdalla EK, Kopetz S, Garrett CR, Overman MJ, Eng C, Andreou A, Loyer EM, Madoff DC, Curley SA, Vauthey JN.

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Title - Change Me

Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified?
Brouquet A, Overman MJ, Kopetz S, Maru DM, Loyer EM, Andreou A, Cooper A, Curley SA, Garrett CR, Abdalla EK, Vauthey JN.

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Title - Change Me

Association of mannose-binding lectin-2 gene polymorphism with the development of hepatitis C-induced hepatocellular carcinoma
Eurich D, Boas-Knoop S, Morawietz L, Neuhaus R, Somasundaram R, Ruehl M, Neumann UP, Neuhaus P, Bahra M, Seehofer D.

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Title - Change Me

2010

Monitoring of liver cell transplantation in a preclinical swine model using Magnetic Resonance Imaging
N. Raschzok, U. Teichgräber, N. Billecke, A. Zielinski, K. Steinz, N.N. Kammer, M.H. Morgul, S. Schmeisser, M.K. Adonopoulou, L. Morawietz, B. Hiebl, R. Schwartlander, W. Rüdinger, B. Hamm, P. Neuhaus, I.M. Sauer

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Title - Change Me

Preoperative multidetector row computed tomography for evaluation and assessment of resection criteria in patients with pancreatic masses
Grieser C, Steffen IG, Grajewski L, Stelter L, Streitparth F, Schnapauff D, Glanemann M, Langrehr J, Andreou A, Neuhaus P, Hamm B, Hänninen EL, Denecke T.

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Title - Change Me

Distal pancreatectomy with splenectomy and en bloc resection of the celiac trunk for locally advanced cancer of the pancreatic body with infiltration of the celiac trunk
Andreou A, Glanemann M, Guckelberger O, Denecke T, Grieser C, Podrabsky P, Neuhaus P.

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Title - Change Me

Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro 
A. Diestel, S. Troeller, N. Billecke, I.M. Sauer, F. Berger, K.R.L. Schmitt

European Journal of Neuroscience, 2010; 31: 779-787

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Title - Change Me

Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its value as a serum marker in hepatocellular carcinomas
Riener MO, Stenner F, Liewen H, Soll C, Breitenstein S, Pestalozzi BC, Samaras P, Probst-Hensch N, Hellerbrand C, Müllhaupt B, Clavien PA, Bahra M, Neuhaus P, Wild P, Fritzsche F, Moch H, Jochum W, Kristiansen G.

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Title - Change Me

Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its value as a serum marker in hepatocellular carcinomas
Riener MO, Stenner F, Liewen H, Soll C, Breitenstein S, Pestalozzi BC, Samaras P, Probst-Hensch N, Hellerbrand C, Müllhaupt B, Clavien PA, Bahra M, Neuhaus P, Wild P, Fritzsche F, Moch H, Jochum W, Kristiansen G.

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Title - Change Me

Nonresponse to pre-operative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases
Neumann UP, Thelen A, Röcken C, Seehofer D, Bahra M, Riess H, Jonas S, Schmeding M, Pratschke J, Bova R, Neuhaus P.

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Title - Change Me

High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro in vivo
Lehmann A, Denkert C, Budczies J, Buckendahl AC, Darb-Esfahani S, Noske A, Müller BM, Bahra M, Neuhaus P, Dietel M, Kristiansen G, Weichert W.

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Title - Change Me

Tacrolimus and methylprednisolone prevent hypothermia induced endothelial dysfunction
A. Diestel, N. Billecke, J. Roessler, B. Schmitt, S. Troeller, R. Schwartlander, F. Berger, I.M. Sauer*, K.R.L. Schmitt*

Journal of Heart and Lung Transplantation, 2009, 28: 718-724 (IF: 3.514)

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Title - Change Me

Somatostatin receptor subtype-2-deficient mice with diet-induced obestiy have hyperglycemia, non-fasting hyperglucagonemia and decreased hepatic glycogen deposition
V. Singh, C. Grotzinger, K.W. Nowak, S. Zacharias, E. Goncz, G. Pless, I.M. Sauer, I. Eichhorn, B. Pfeiffer-Guglielmi, B. Hamprecht, B. Wiedenmann, U. Plockinger, M.Z. Strowski

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Title - Change Me

Combination therapy of poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide and gemcitabine shows strong antitumor activity in pancreatic cancer cells
Jacob DA, Bahra M, Langrehr JM, Boas-Knoop S, Stefaniak R, Davis J, Schumacher G, Lippert S, Neumann UP.

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Title - Change Me

Peroxisome proliferator-activated receptor gamma is highly expressed in pancreatic cancer and is associated with shorter overall survival times
Kristiansen G, Jacob J, Buckendahl AC, Grützmann R, Alldinger I, Sipos B, Klöppel G, Bahra M, Langrehr JM, Neuhaus P, Dietel M, Pilarsky C.

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Title - Change Me

Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells
Jacob D, Schumacher G, Bahra M, Davis J, Zhu HB, Zhang LD, Teraishi F, Neuhaus P, Fang BL.

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Title - Change Me

In vitro evaluation of the transportability of viable primary human liver cells originating from discarded donor organs in bioreactors
I.M. Sauer, R. Schwartlander, O. van der Jagt, I. Steffen, E. Efimova, G. Pless, D.C. Kehr, D. Kardassis, J.H. Fruhauf, J.C. Gerlach, P. Neuhaus

Artificial Organs 2005, 29: 141-151 (IF: 1.946)

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Title - Change Me

2003

The use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors – a morphological study
J.C. Gerlach, K. Mutig, I.M. Sauer, P. Schrade, E. Efimova, T. Mieder, G. Nauman, A. Grünwald, G. Pleß, A. Mas, S. Bachmann, P. Neuhaus, K. Zeilinger

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Title - Change Me

Einsatz biologischer Leberunterstützungssysteme bei der Therapie des Leberversagens – Modular Extracorporeal Liver Support (MELS)
T.P. Theruvath, I.M. Sauer, D. Kardassis, N. Obermayer, A. Pascher, M. Goetz, A.R. Mueller, Th. Steinmueller, P. Neuhaus, J.C. Gerlach

Verdauungskrankheiten 2003, 21: 32-40

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Title - Change Me

Primary human liver cells as source for modular extracorporeal liver support – a preliminary report
I.M. Sauer, K. Zeilinger, N. Obermayer, G. Pless, A. Pascher, T. Mieder, S. Roth, M. Goetz, D. Kardassis, A. Mas, P. Neuhaus, J.C. Gerlach

International Journal of Artificial Organs 2002, 25: 1001-1005 (IF: 1.192)

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Title - Change Me

Analysis of allogeneic versus xenogeneic auxiliary organ perfusion in liver failure reveals superior efficacy of human livers
A. Pascher, I.M. Sauer, P. Neuhaus

International Journal of Artificial Organs 2002, 25: 1006-1012 (IF: 1.192)

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Title - Change Me

Modified surgical technique in clinical small bowel transplantation: donor and recipient management.
A. Mueller, A. Pascher, K. Platz, N. Nussler, R. Schulz,D. Horch,T. Melitz,I. M. Sauer, R. Eisele,U. Settmacher,A. Dignass,E. Lopez-Henninen,H. Weidemann,P. Neuhaus

Transplantation Proceedings 2002; 34: 2265 (IF: 0.478)

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Title - Change Me

Living-Donation Liver Transplantation for Hepatocellular Carcinoma: Time to Drop the Limitations?
Th. Steinmüller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Müller, U.Settmacher, P. Neuhaus

Transplantation Proceedings 2002; 34: 2263-2264 (IF: 0.478)

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Title - Change Me

Use of inferior mesenteric vein for venous anastomosis in clinical small bowel transplantation.
K.P. Platz, A. Pascher, R.J. Schulz, N.C. Nussler, I.M. Sauer, U. Settmacher, R. Eisele, A. Dignass, E. Lopez-Henninen, P. Neuhaus, A.R. Mueller

Transplantation Proceedings 2002, 34: 906-907 (IF: 0.478)

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Title - Change Me

Monitoring of immunosuppression after clinical small bowel transplantation.
A. Pascher, I.M. Sauer, R.J. Schulz, K. Platz, T. Theruvath, A. Dignass, C. Radke, P. Neuhaus, A.R. Mueller

Transplantation Proceedings 2002, 34: 931-933 (IF: 0.478)

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Title - Change Me

Modular Extracorporeal Liver Support (MELS) bei Leberversagen
D. Kardassis, T.P. Theruvath, I.M. Sauer, J.C. Gerlach, P. Neuhaus

Journal für Anästhesie und Intensivbehandlung 2001, 3: 97-99

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Title - Change Me

Split liver and living donation liver transplantation: the Berlin experience.
I.M. Sauer, A. Pascher, Th. Steinmueller, U. Settmacher, A.R. Müller, W.O. Bechstein, P. Neuhaus

Transplantation Proceedings 2001; 33: 1459-1460 (IF: 0.568)

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Title - Change Me

2021

Adaptivität – die Zukunft digitaler Bildgebung? In: Adaptivität (Editors: M. Queisner, M. Bruhn, K. Friedrich, l. Kähny ) Hildesheim, Zürich, New York: Olms Weidmann
M. Queisner, M. Bruhn, K. Friedrich

Szenarien adaptiver Bildgebung In: Adaptivität (Editors: M. Queisner, M. Bruhn, K. Friedrich, l. Kähny ) Hildesheim, Zürich, New York: Olms Weidmann
M. Queisner, M. Bruhn, K. Friedrich, L. Kähny

Was sind adaptive Bilder? In: Adaptivität (Editors: M. Queisner, M. Bruhn, K. Friedrich, l. Kähny ) Hildesheim, Zürich, New York: Olms Weidmann
M. Queisner, M. Bruhn, K. Friedrich

2019

Engineering an endocrine Neo-Pancreas. In: Decellularized Extracellular Matrix: Characterization, Fabrication and Applications (Editors: Tetsuji Yamaoka, Takashi Hoshiba)
E. Keshi, I.M. Sauer, K.H. Hillebrandt

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Title - Change Me

2017

Preclinical swine models for monitoring of hepatocyte transplantation by MRI Hepatocyte Transplantation – Methods and Protocols (Editors: Stock, Christ)
N. Raschzok, U. Teichgräber, J. Pratschke, I.M. Sauer

Springer Verlag, 2017 (ISBN: 978-1-4939-6506-9)

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Title - Change Me

2014

Extracorporeal Liver Support, Liver-Cell Transplantation, and Bioengineered Substitutes. In: Textbook of Organ Transplantation (Editors: Kirk, Knechtle, Larsen, Pearson, Webber)
I.M. Sauer, N. Raschzok, P. Neuhaus

Wiley-Blackwell, 2014 (ISBN: 978-1-118-87014-3)

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Title - Change Me

2009

Extracorporeal liver support. In: Management of acute kidney problems (Editors: Ronco, Kellum, Jörres)
I.M. Sauer

Springer Verlag, 2009 (ISBN: 978-3-540-69413-7)

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Title - Change Me

Akutes Nierenversagen bei Intensivpatienten: Extrakorporale Leberersatzverfahren (Editor: Jörres)
G. Pless, I.M. Sauer

Deutscher Ärzte Verlag, 2009 (ISBN 978-3-7691-0477-6)

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Title - Change Me

2006

Hybride Organe: Künstliche und zellbasierte Leberunterstützungssysteme. In: Chirurgische Forschung (Editors: Krukemeyer, Spiegel)
I.M. Sauer, P. Neuhaus

Georg Thieme Verlag, 2006: 366-378 (ISBN: 3-13-133661-7)

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Title - Change Me

2005

Modular Extracorporeal Liver Support. In: Artificial Liver Support (Editors: Henne-Bruns, Buttenschön, Fuchs, Lohse) Falk-Symposium, Vol. 145, 2005
I.M. Sauer

Springer Verlag, 2005: 53-60 (ISBN: 1-4020-3239-0)

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Title - Change Me

Extrakorporale Leberunterstützungssysteme. In: Aktuelle Aspekte der Lebertransplantation (Editors: Neuhaus, Pfitzmann)
G. Puhl, I.M. Sauer

UniMed-Verlag, 2. Edition, 2005: 60-69 (ISBN 3-89599-774-9)

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Title - Change Me

2001

Liver Transplantation. In: Surgical treatment. Evidence-based and problem-oriented (Editor: Mannick)
I.M. Sauer, W.O. Bechstein, P. Neuhaus

Zuckschwerdt Verlag, München, Bern, Wien, New York: 298-305 (ISBN: 3-88603-714-2)

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Title - Change Me

Bioartificial Organs III: Tissue Sourcing, Immunoisolation, and Clinical Trials (Editors: Hunkeler, Cherrington, Prokop, and Rajotte)
I.M. Sauer, N. Obermayer, D. Kardassis , T. Theruvath and J.C. Gerlach

Annals of the New York Academy of Sciences 2001, 944: 308-320 (ISBN: 1-57331-342-4)

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Title - Change Me

2000

Hepatozyten-Tissue Engineering und Bioreaktoren für hybride Leberunterstützungssysteme (Editor: Encke)
I.M. Sauer, J.C. Gerlach, P. Neuhaus

Deutsche Gesellschaft für Chirurgie – Kongressband 2000 : 764-769

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Title - Change Me

Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay
Arnold A, Bahra M, Lenze D, Bradtmöller M, Guse K, Gehlhaar C, Bläker H, Heppner FL, Koch A. 

Deutsche Gesellschaft für Chirurgie – Kongressband 2000 : 764-769

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