Effect of virtual reality on spatial-anatomical understanding in preoperative liver surgery: a randomized crossover study
A. Zolkin, C. Rüger, C. Remde, Z. Akbal, M.M. Maurer, N. Raschzok, J. Pratschke, I.M. Sauer, M. Queisner
Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.
Effect of virtual reality on spatial-anatomical understanding in preoperative liver surgery: a randomized crossover study
A. Zolkin, C. Rüger, C. Remde, Z. Akbal, M.M. Maurer, N. Raschzok, J. Pratschke, I.M. Sauer, M. Queisner
Impact of Hematocrit on Normothermic Machine Perfusion of Rat Liver Grafts and Viability Testing
J.R. Bornemann, L. Gilles, V. Appel, S. Moosburner, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
Isolation of functional human islets from pancreatectomy remnants: Determinants of yield and functionality
K.H. Hillebrandt, T. Lohmann, L. Haderer, S. Moosburner, M. Felsenstein, L.Ä. Böhne, A. Arnold, A. Reutzel-Selke, J. Pratschke, T. Malinka, I.M. Sauer, E. Keshi
Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity
W. Zhao, L.M. Skrip, H. Tzschätzsch, T. Meyer, H.S. Aghamiry, A. Arnold, L.Ä. Böhne, J. Jordan, O. Boehm, A.K. Boehm, S. Görner, J. Schattenfroh, Y. Wu, P.A.D. de Moraes, J. Pratschke, J. Braun, I.M. Sauer, J. Guo, I. Sack, K.H. Hillebrandt
Proteomic profiling of colorectal liver metastases reveals histopathological response-specific molecular signatures of chemotherapy efficacy
A.K. Böhm, L.M. Skrip, D. Klein, F. Strobl, J.K. Wieland, A. Arnold, Y. Zhou, B. Papke, C. Sers, D.P. Modest, S. Moosburner, P.K. Haber, F. Krenzien, N. Raschzok, W. Schöning, D. Horst, T. Malinka, I. Sack, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Virtual reality volumetric rendering versus cross-sectional imaging for pancreatic cancer resectability assessment: a pilot randomized controlled reader study
K. Eisenträger, K. Saribeyoglu, U. Fehrenbach, M. Felsenstein, L. Timmermann, P.L.M. Pereira, W. Schöning, B. Strücker, J. Pratschke, A. Pascher, T. Malinka, I.M. Sauer, H. Morgul, M. Queisner
Impact of Donor Age and Prolonged Warm Ischemia in Normothermic Machine Perfusion of Rat Livers
A.S. Pietsch, L. Boerger, L. Padoan, K.A. Walter, J.M. Gassner, O. Klein O, L.A. Böhne, A. Arnold, D. Horst, I. Iske, K.H. Hillebrandt, F. Krenzien, J. Pratschke, I.M. Sauer, N. Raschzok, S. Moosburner
Overcoming the data barrier: transfer learning for 90-day mortality prediction in general surgery - a retrospective multicenter development and comparison study
A. Winter, B. Pfitzner, R.P. van de Water, L. Faraj, C. Riepe, W.H. Hahn, F. Krenzien, C. Schineis, T. Malinka, W. Schöning, C. Denecke, B. Arnrich, K. Beyer, J. Pratschke, I.M. Sauer, M.M. Maurer
Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection
A.M. Pfefferkorn, L. Jahn, P.T. Gauthier, V.A. Kulow, J. Roeles, N. Müller-Bötticher, L.M.S. Gerhardt, J. Leiz, S. Sarfraz, I. Plumbom, R. Greite, S. Lovric, J. Gamrekelashvili, F. Limbourg, J. Schmitz, J.M. Bräsen, I. Scheffner, I.M. Sauer, F. Aigner, J. Altmüller, T. Conrad, W. Gwinner, N. Ishaque, M. Fähling, K.M. Schmidt-Ott, P.F. Halloran, M.I. Ashraf, C. Hinze
Targeting the stromal-immune barrier: A novel strategy to overcome resistance to CLDN18.2/CD3 bispecific T-cell engager therapy in pancreatic cancer
S. Liu, M. Felsenstein, S. Liu, I.M. Sauer, M.I. Ashraf
Comparison of different decellularization protocols for porcine centrum tendineum diaphragmatis and diaphragmatic muscle – a base for effective recellularization
B.F. Gaag, P. Tang, O. Klein, S. Moosburner, A.K. Böhm, T. Lohmann, J.K. Wieland, V. Contes, Y. Zhou, E. Keshi, L. Haderer, E. Metzler, V. Schöwel-Wolf, S. Spuler, J.C. Rückert, J. Pratschke, I.M. Sauer, M.N. Andreas, K.H. Hillebrandt
Assessing age and cold ischemia effects on liver tissue viscoelastic properties: Implications for graft quality assessment with MRE during machine perfusion
L.M. Skrip, L. Boerger, K.A. Walter, A. Arnold, L.A. Böhne, E. Keshi, A.S. Pietsch, N. Raschzok, T.A. Auer, U. Fehrenbach, F. Krenzien, J. Pratschke, I.M. Sauer, J. Guo, J. Braun, H. Tzschätzsch, I. Sack, K.H. Hillebrandt, S. Moosburner
Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants
A.M. Pfefferkorn, R. Fritsche-Guenther, A. Kusch, H. Schwelberger, S. Liu, R. Klopfleisch, Y. Li, R. Catar, S. Liu, F. Aigner, J. Pratschke, I.M. Sauer, M.I. Ashraf
Prototype of a Virtual Reality Simulator for Thyroidectomy: A Proof of Concept
K. Eisentraeger, E.M. Dobrindt, M. Queisner, C. Remde, I.M. Sauer, J. Pratschke, M. Mogl, F. Butz, C. Müller-Debus
Privacy preserving federated learning for 90-day mortality prediction in colorectal surgery: a multicenter retrospective development and comparison study
M.M. Maurer, B. Pfitzner, R.P. van de Water, L. Faraj, C. Riepe, D. Zuluaga, F. Krenzien, N. Raschzok, R. Siegel, C. Schineis, B. Arnrich, K. Beyer, J. Pratschke, I.M. Sauer, A. Winter
Technical Recommendation on Multi-Driver Multifrequency MR Elastography for Tomographic Mapping of Abdominal Stiffness With a Focus on the Pancreas and Pancreatic Ductal Adenocarcinoma
J. Schattenfroh, S. Almutawakel, J. Bieling, J. Castelein, M. Estrella, P. Garteiser, V. Hartung, K.H. Hillebrandt, A.T. Huber, L. Körner, t. Kröncke, T. Malinka, H.J. Meyer, T. Meyer, U. Pelzer, F. Pfister, I.M. Sauer, A. Speth, B.E. Van Beers, C. Warmuth, N.P.M. Wassenaar,Y. Wu, R.O. Reiter, I. Sack ; European Consortium of MRE in PDAC
90-Day mortality prediction in elective visceral surgery using machine learning: a retrospective multicenter development, validation and comparison study
C. Riepe, R. van de Water, A. Winter, B. Pfitzner, L. Faraj, R. Ahlborn, M. Schulze, D. Zuluaga, C. Schineis, K. Beyer, J. Pratschke, B. Arnrich, I.M. Sauer, M.M. Maurer
Lipocalin-2 Restores Soluble Guanylyl Cyclase-Dependent Dilation of the Afferent Arteriole After Renal Transplantation or Ex Vivo Hypoxia/Reoxygenation in Mice
L. Zhao, M. Xu, A.M. Pfefferkorn, C. Erdogan, H. Schwelberger, P. Wang, P.H. Khedkar, M. Eigen, F.B. Lichtenberger, R. Catar, E.Y Lai, F. Aigner, P.B. Persson, I.M. Sauer, A. Patzak, M.I. Ashraf
Human-Centered Design of Mixed Reality Applications in Medical Education – GreifbAR
R. Luzsa, M. Queisner, Ch. Remde, I. Sauer, N. Robertini, S. Mayr
Enhanced anti-tumor activity by zinc finger repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs
M. David, P. Schiele, D. Monteferrario, G. Saviane, A.E. Martelli, C.F. Dupont, C. Jeanneau, I. Marchetti, S.K. Tadi, J. Vahldick, L.N. Truong, Y. Zhou, I.M. Sauer, W. Schöning, I.-K. Na, A. Reik, M. Frentsch, M. Rosa, D. Fenard
Sparse camera volumetric video applications. A comparison of visual fidelity, user experience, and adaptability
Ch. Remde, I.M. Sauer, M. Queisner
Oncological Operation Notes: Minimum Requirements, Legal Aspects, and Future Developments
J. Klose, S. Böhm, Ch. Bruns, P. Chojecki, L.-Ch. Conradi, S. Fichtner-Feigl, R. Grützmann, J. Heberer, B. Jansen-Winkeln, J. Jakob, K. Kohlhaw, A. Oehme, U. Ronellenfitsch, S. Roth, Ch. Rüger, I. Sauer, H. Schulz, S. Zehnder, J. Kleeff
Chirurgie, 2025 – in press
Extracellular NAD+ levels are associated with CD203a expression on Th17 cells and predict long-term recurrence-free survival in hepatocellular carcinoma
J. Babigian J, P. Brunnbauer, C. Kamali, S. Knitter, E. Keshi, M. Felsenstein, P. Haber, I. Lozzi, W. Schöning, J. Pratschke, F. Krenzien
Gender-based variations in surgical management of colorectal liver metastases: comprehensive analysis
P.F. Koch, K. Ludwig, K.H. Hillebrandt, H. Freitag, M. Blank, S. Knitter, D.P. Modest, F. Krenzien, G. Lurje, W. Schöning, J. Pratschke, I.M. Sauer, S. Moosburner, N. Raschzok
Cytokine-armed vaccinia virus promotes cytotoxicity towards pancreatic carcinoma cells via activation of human intermediary CD56dimCD16dim natural killer cells
R. Wang, M. Hu, I. Lozzi, C.Z.J. Jin, D. Ma, K. Splith, J. Mengwasser, V. Wolf, L. Feldbrügge, P. Tang, L. Timmermann, K.H. Hillebrandt, M. Kirchner, Ph. Mertins, G. Hilfenhaus, Ch. Neumann, Th. Kammertoens, J. Pratschke, T. Malinka, I. Sauer, E. Nössner, Z. Guo, M. Felsenstein
Comment on "Endotoxin, not DNA, determines the host response and tissue regeneration behavior of acellular biologic scaffolds"
E. Keshi, I.M. Sauer, K. Hillebrandt
Thrombogenicity assessment of perfusable tissue engineered constructs: a systematic review
L.M. Haderer, Y. Zhou, P. Tang, A. Daneshgar, B. Globke, F. Krenzien, A. Reutzel-Selke, M. Weinhart, J. Pratschke, I.M. Sauer, K.H. Hillebrandt, E. Keshi
Quality assessment by bile composition in normothermic machine perfusion of rat livers
V. Muth, F. Stobl, J. Michelotto, J.A. Kirwan, J. Marchand, N.N. Roschke, S. Moosburner, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
A new bicornuate model of rat uterus transplantation
D. Polenz, I.M. Sauer, F. Martin, A. Reutzel-Selke, M.I. Ashraf, A. Schirmeier, S. Lippert, K. Führer, J. Pratschke, S.G. Tullius, S. Moosburner.
Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients
P. Schiele, S. Kolling, S. Rosnev, Ch. Junkuhn, A.L. Walter, J.Ch. von Einem, S. Stintzing, W. Schöning, I.M. Sauer, D.P. Modest, K. Heinrich, L. Weiss, V. Heinemann, L. Bullinger, M. Frentsch, I.-K. Na
Viscoelastic properties of colorectal liver metastases reflect the tumour cell viability
L.-M. Skrip, S. Moosburner, P. Tang, J. Guo, S. Görner, H. Tzschätzsch, C. Hosse, U. Fehrenbach, A. Arnold, D. Modest, F. Krenzien, W. Schöning, Th. Malinka, J. Pratschke, B. Papke, J.A. Käs, I. Sack, I.M. Sauer, K.H. Hillebrandt
Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma
I. Lozzi, A. Arnold, M. Barone, J.C. Johnson, B.V. Sinn, J. Eschrich, P. Gebert, R. Wang, M. Hu, L. Feldbrügge, A. Schirmeier, A. Reutzel-Selke, T. Malinka, F. Krenzien, W. Schöning, D.P. Modest, J. Pratschke, I.M. Sauer, M. Felsenstein
Extracellular NAD+ Response to Post-Hepatectomy Liver Failure: Bridging Preclinical and Clinical Findings
C. Kamali, P. Brunnbauer, K. Kamali, Al-H. Saqr, A. Arnold, G. Harman Kamali, J. Babigian, E. Keshi, R. Mohr, M. Felsenstein, S. Moosburner, K. Hillebrandt, J. Bartels, I. Sauer, F. Tacke, M. Schmelzle, J. Pratschke, F. Krenzien
Induced pluripotent stem cell (iPSC) line (EXSURGi001-A) from a patient homozygous for the p.Ala165Thr mutation in the MTARC1 gene
P. Tang, E. Keshi, S. Wilken, L. Wutsdorff, J. Mougnekabol, J. Pratschke, I.M. Sauer N. Haep
Distinctive protein expression in elderly livers in a Sprague-Dawley rat model of normothermic ex vivo liver machine perfusion
M. Zimmer, K.H. Hillebrandt, N.M. Roschke, S. Lippert, O. Klein, G. Nebrich, J.M.G.V. Gassner, F. Strobl, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner
Multinational Analysis of Marginal Liver Grafts Based on the Eurotransplant Extended Donor Criteria
S. Moosburner, M.S. Patel, B.K. Wang, J. Prasadh, R. Öllinger, G. Lurje, I.M. Sauer, P.A. Vagefi, J. Pratschke, N. Raschzok
Comment on "Impact of Back-to-Base Normothermic Machine Perfusion on Complications and Costs: A Multi-Center, Real-World Risk-Matched Analysis"
K.A. Walter, M.S. Patel, I.M. Sauer, J. Pratschke, N. Raschzok, S. Moosburner
On the relationship between viscoelasticity and water diffusion in soft biological tissues
J. Braun, J. Bernarding, J. Snellings, T. Meyer, P.A. Dantas de Moraes, Y. Safraou, R.G. Wells, J. Guo, H. Tzschätzsch, A. Zappe, K. Pagel, I.M. Sauer, K.H. Hillebrandt, I. Sack
Chemistry matters: A side-by-side comparison of two chemically distinct methacryloylated dECM bioresins for vat photopolymerization
A. Almalla, L. Elomaa, N. Fribiczer, T. Landes, P. Tang, Z. Mahfouz, B. Koksch, K.H. Hillebrandt, I.M. Sauer, D. Heinemann, S. Seiffert, M. Weinhart
Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants
M.I. Ashraf, J. Mengwasser, A. Reutzel-Selke, D. Polenz, K. Führer, S. Lippert, P. Tang, E. Michaelis, R. Catar, J. Pratschke, Ch. Witzel, I.M. Sauer, S.G. Tullius, B. Kern
Surgical planning in virtual reality: a systematic review
M. Queisner, K. Eisenträger
Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome
N.N. Roschke, K.H. Hillebrandt, D. Polenz, O. Klein, J.M.G.V. Gassner, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner.
Proteomic analysis of decellularized mice liver and kidney extracellular matrices
A.M. Diedrich, A. Daneshgar, P. Tang, O. Klein, A. Mohr, O.A. Onwuegbuchulam, S. von Rueden, K. Menck, A. Bleckmann, M.A. Juratli, F. Becker, I.M. Sauer, K.H. Hillebrandt, A. Pascher, B. Struecker
miRNA as potential biomarkers after liver transplantation: A systematic review
P.F. Koch, K. Ludwig, F. Krenzien, K.H. Hillebrandt, W. Schöning, J. Pratschke, N. Raschzok, I.M. Sauer, S. Moosburner
Improved outcomes after hypothermic oxygenated machine perfusion in liver transplantation-Long-term follow-up of a multicenter randomized controlled trial.
Z. Czigany, D. Uluk, S. Pavicevic, I. Lurje, J. Froněk, Th. Keller, P. Strnad, D. Jiang, T. Gevers, D. Koliogiannis, M. Guba, R.H. Tolba, F.A. Meister, U.P. Neumann, M. Kocik, M. Kysela, I.M. Sauer, N. Raschzok, W. Schöning, I. Popescu, F. Tacke, J. Pratschke, G. Lurje
Towards a 3D-printed perfusable islet embedding structure: technical notes and preliminary results
E. Keshi, P. Tang, T. Lam, S. Moosburner, L.M. Haderer, A. Reutzel-Selke, L. Kloke, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels
A. Almalla, L. Elomaa, L. Bechtella, A. Daneshgar, P. Yavvari, Z. Mahfouz, P. Tang, B. Koksch, I. Sauer, K. Pagel, K.H. Hillebrandt, M. Weinhart
Redefining the Laparoscopic Spatial Sense: AI-based Intra- and Postoperative Measurement from Stereoimages
L. Müller, P. Hemmer, M. Queisner, I. Sauer, S. Allmendinger, J. Jakubik, M. Vössing, N. Kühl
Rise of tissue- and species-specific 3D bioprinting based on decellularized extracellular matrix-derived bioinks and bioresins
L. Elomaa, A. Almalla, E. Keshi, K.H. Hillebrandt, I.M. Sauer, M. Weinhart
Moderate LMWH anticoagulation improves success rate of hind limb allotransplantation in mice
B. Kern, M.-I. Ashraf, A. Reutzel-Selke, J. Mengwasser, D. Polenz, E. Michaelis, J. Pratschke, S.G. Tullius, Ch. Witzel, I.M. Sauer
Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering
M.N. Andreas, A.K. Boehm, P. Tang, S. Moosburner, O. Klein, A. Daneshgar, J.M.G.V. Gaßner, N. Raschzok, D. Wulsten, J.-C. Rückert, S. Spuler, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Advancing perfusion models: Dual-vessel ex vivo rat liver perfusion based on a clinical setup
F. Strobl, J. Michelotto, V. Muth, S. Moosburner, K. Knaub, M. Zimmer, M. Patel, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
How many liver transplantations could be recovered after implementation of donation after cardiac death in Germany?
S. Moosburner, I.M. Sauer, B. Weiß, J. Pratschke, N. Raschzok
Body composition is associated with disease aetiology and prognosis in patients undergoing resection of intrahepatic cholangiocarcinoma.
I. Lurje, D. Uluk, S. Pavicevic, M.D. Phan, D. Eurich, U. Fehrenbach, D. Geisel, T.A. Auer, U. Pelzer, D.P. Modest, N. Raschzok, I.M. Sauer, W. Schöning, F. Tacke, J. Pratschke, G. Lurje G
Validation of risk scores for allograft failure after liver transplantation in Germany: a retrospective cohort analysis
S. Moosburner, L. Wiering, N. Roschke, A. Winter, Axel; M. Demir, J.M.G.V. Gaßner, M. Zimmer, P. Ritschl, B. Globke, G. Lurje, F. Tacke, W. Schöning, J. Pratschke, R. Öllinger, I.M. Sauer, N. Raschzok
MR Elastography in Cancer
J. Guo, L.J. Savic, K.H. Hillebrandt, I. Sack
Bioactive photocrosslinkable resin solely based on refined decellularized small intestine submucosa for vat photopolymerization of in vitro tissue mimics
L. Elomaa, L. Gerbeth, A. Almalla, N. Fribiczer, A. Daneshgar, P. Tang, K. Hillebrandt, S. Seiffert, I.M. Sauer, B. Siegmund, M. Weinhart
Augmenting Image-Guided Procedures through In Situ Visualization of 3D Ultrasound via a Head-Mounted Display
F. von Haxthausen, Ch. Rüger, M.M. Sieren, R. Kloeckner, F. Ernst
Effect of pre-operative chemotherapy on the isolation outcome of primary human hepatocytes
M. Rissel, J. Pohl, S. Moosburner, J. Gaßner, R. Horner, K. Hillebrandt, D. Modest, J. Pratschke, I.M. Sauer, N. Raschzok
Inhibition of Vascular Endothelial Growth Factor Protects against the Development of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome in Wild-Type but Not in CD39-Null Mice
S. Knitter, G. Duwe, A.S. Beierle, S. Pesthy, P.V. Ritschl, K.H. Hillebrandt, A. Arnold, T. Malinka, D.P. Modest, M. Bahra, J. Pratschke, I.M. Sauer, M. Schmelzle, A. Andreou
Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues
J. Snellings, E. Keshi, P. Tang, A. Daneshgar, E.C. Willma, L. Haderer, O. Klein, F. Krenzien, Th. Malink, P. Asbach, J. Pratschke, I.M. Sauer, J. Braun, I. Sack, K. Hillebrandt
Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models
V. Muth, J.M.G.V. Gassner, S. Moosburner, G. Lurje, J. Michelotto, F. Strobl, K. Knaub, C. Engelmann, F. Tacke, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok N
Tissue engineering for the diaphragm and its various therapeutic possibilities – A Systematic Review
A.K. Boehm, K.H. Hillebrandt, T. Dziodzio, F. Krenzien, J. Neudecker, S. Spuler, J. Pratschke, I.M. Sauer, M.N. Andreas
VolumetricOR: A new Approach to Simulate Surgical Interventions in Virtual Reality for Training and Education
M. Queisner, M. Pogorzhelskiy, Ch. Remde, J. Pratschke, I.M. Sauer
Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies?
M. Felsenstein, F. Lindhammer, M. Feist, K.H. Hillebrandt, L. Timmermann, C. Benzing, B. Globke, D. Zocholl, M. Hu, U. Fehrenbach, B.V. Sinn, U. Pelzer, I.M. Sauer, J. Pratschke, T. Malinka
Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing
J.M. Alves, S. Prado-López, L. Tomás, M. Valecha, N. Estévez-Gómez, P. Alvariño, D. Geisel, D.P. Modest, I.M. Sauer, J. Pratschke, N. Raschzok, C. Sers, S. Mamlouk, D. Posada
Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next-Generation Outcome Prediction in Transplantation Medicine
S. Moosburner, J.M.G.V. Gassner, J. Pratschke, I.M. Sauer, N. Raschzok
Prognostic and Predictive Molecular Markers in Cholangiocarcinoma
S. Pavicevic, S. Reichelt, D. Uluk, I. Lurje, C. Engelmann, D.P. Modest, U. Pelzer, F. Krenzien, N. Raschzok, C. Benzing, I.M. Sauer, S. Stintzing, F. Tacke, W. Schöning, M. Schmelzle, J. Pratschke, G. Lurje
FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer
N. Raschzok, S. Stintzing, V. Heinemann, G. Rauch, J. Ricke, M. Guckenberger, A. Kurreck, A.H.S. Alig, A. Stahler, L. Bullinger, M. Schmelzle, W. Schöning, G. Lurje, F. Krenzien, O. Haase, B. Rau, B. Gebauer, I.M. Sauer, J. Pratschke, D.P. Modest DP
Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
N. Krause, J. Mengwasser, E. Phithak, F. Beato, M. Appis, E.L. Milford, J. Pratschke J, I. Sauer, A. Kuehl, A. Vogel, M. Goodyear, L. Hammerich, F. Tacke, J.F. Haas, T. Müller, N. Utku N
[Digital documentation of complications in visceral surgery: possibilities and evaluation of an instrument for quality management]
A. Winter, M.M. Maurer, M. Schmelzle, T. Malinka, M. Biebl, P. Fikatas, D. Kröll, I.M. Sauer, M. Hippler-Benscheidt, J, Pratschke, S. Chopra
Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity
E. Keshi, P. Tang, M. Weinhart, H. Everwien, S. Moosburner, N. Seiffert, M. Lommel, U. Kertzscher, B. Globke, A. Reuztel-Selke, B. Strücker, J. Pratschke, I.M. Sauer, N. Haep, K.H. Hillebrandt
Cancer Associated Fibroblasts Derived from Pancreatic Adenocarcinoma and Their Role in Cell Migration
E. von Hoerschelmann, C.C.M. Neumann, M. Felsenstein, J. Gogolok, A. Reutzel-Selke, I.M. Sauer, J. Pratschke, M. Bahra, R.B, Schmuck
Perioperative Risk Assessment in Pancreatic Surgery Using Machine Learning
B. Pfitzner, J. Chromik, R. Brabender, E. Fischer, A. Kromer, A. Winter, S. Moosburner, I.M. Sauer, T. Malinka, J. Pratschke, B. Arnrich, M.M. Maurer
A Note on Neurosurgical Resection and Why We Need to Rethink Cutting
T. Picht, M.L. Calvé, R. Tomasello, L. Fekonja, M.F. Gholami, M. Bruhn, C. Zwick, J.P. Rabe, C. Müller-Birn, P. Vajkoczy, I.M. Sauer, S. Zachow, J.A. Nyakatura, P. Ribault, F. Pulvermüller
Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies
S. Gül-Klein, H. Hegermann, R. Röhle, M. Schmelzle, F. Tacke, W. Schöning, R. Öllinger, T. Dziodzio, P. Maier, J.M. Plewe, D. Horst, I.M. Sauer, J. Pratschke, N. Lachmann, D. Eurich
Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study
K. Kamali, M. Schmelzle, C. Kamali, P. Brunnbauer, K. Splith, A. Leder, N. Berndt, K.H. Hillebrandt, N. Raschzok, L. Feldbrügge, M. Felsenstein, J. Gaßner, P. Ritschl, G. Lurje, W. Schöning, C. Benzing, J. Pratschke, F. Krenzien
In vitro recellularization of decellularized bovine carotid arteries using human endothelial colony forming cells
N. Seiffert, P. Tang, E. Keshi, A. Reutzel-Selke, S. Moosburner, H. Everwien, D. Wulsten, H. Napierala, J. Pratschke, I.M. Sauer, K. Hillebrandt, B. Struecker
Ex vivo machine perfusion: current applications and future directions in liver transplantation
J. Michelotto, J.M.G.V. Gassner, S. Moosburner, V. Muth, M.S. Patel, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok
Notch Signaling Pathway in Pancreatobiliary Tumors
F. Borlak, A. Reutzel-Selke, A. Schirmeier, J. Gogolok, E. von Hoerschelmann, I.M. Sauer, J. Pratschke, M. Bahra, R.B. Schmuck
Extended liver resection in mice: state of the art and pitfalls – a systematic review
C. Kamali, K. Kamali, P. Brunnbauer, K. Splith, J. Pratschke, M. Schmelzle, F. Krenzien
Engineering an endothelialized, endocrine Neo-Pancreas: Evaluation of islet functionality in an ex vivo model
H. Everwien, E. Keshi, K.H. Hillebrandt, B. Ludwig, M. Weinhart, P. Tang , A.S. Beierle, H. Napierala, J.M. Gassner, N. Seiffert, S. Moosburner, D. Geisel, A. Reutzel-Selke, B. Strücker, J. Pratschke, N. Haep, I.M. Sauer
The Human Liver Matrisome – Proteomic Analysis of Native and Fibrotic Human Liver Extracellular Matrices for Organ Engineering Approaches
A. Daneshgar, O. Klein, G. Nebrich, M. Weinhart, P. Tang, A. Arnold, I. Ullah, J. Pohl, S. Moosburner, N. Raschzok, B. Strücker, M. Bahra, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Early Allograft Dysfunction Increases Hospital Associated Costs After Liver Transplantation-A Propensity Score-Matched Analysis
S. Moosburner, I.M. Sauer, F. Förster, T. Winklmann, J.M.G.V. Gassner, P.V. Ritschl, R. Öllinger, J. Pratschke, N. Raschzok
Ultrasound in augmented reality: a mixed-methods evaluation of head-mounted displays in image-guided interventions
C. Rüger, M.A. Feufel, S. Moosburner, Ch. Özbek, J. Pratschke, I.M. Sauer
The ILLS Laparoscopic Liver Surgery Fellow Skills Curriculum.
F. Krenzien, W. Schöning, P. Brunnbauer, C. Benzing, R. Öllinger, M. Biebl, M. Bahra, N. Raschzok, D. Cherqui, D. Geller, H.S. Han, G. Wakabayashi, M. Schmelzle, J. Pratschke; study group of the International Laparoscopic Liver Society (ILLS)
Declined Liver Grafts - Analysis of the German Donor Population from 2010 to 2018
S. Moosburner, N. Raschzok, C. Schleicher, D. Bösebeck, J.M.G.V. Gaßner, P.V. Ritschl, A. Rahmel, I.M. Sauer, J. Pratschke
Dual versus single vessel normothermic ex vivo perfusion of rat liver grafts using metamizole for vasodilatation
F. Claussen, J.M.G.V. Gassner, S. Moosburner, D. Wyrwal, M. Nösser, P. Tang, L. Wegener, J. Pohl, A. Reutzel-Selke, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
Development of GelMA/PCL and dECM/PCL resins for 3D printing of acellular in vitro tissue scaffolds by stereolithography
L. Elomaa, E. Keshi, I.M. Sauer, M. Weinhart
Extended reality technologies for support of surgical workflows
C. Rüger, S. Moosburner, I.M. Sauer
Innovations in surgery – How can new technologies be safely implemented in the clinical practice?
M. Bahra, J. Pratschke
Increased Cell-Free DNA Plasma Concentration Following Liver Transplantation Is Linked to Portal Hepatitis and Inferior Survival
F. Krenzien, S. Katou, A. Papa, B. Sinn, C. Benzing, L. Feldbrügge, C. Kamali, P. Brunnbauer, K. Splith, R.R. Lorenz, P. Ritschl, L. Wiering, R. Öllinger, W. Schöning, J. Pratschke, M. Schmelzle
The Effects of MELD-Based Liver Allocation on Patient Survival and Waiting List Mortality in a Country with a Low Donation Rate
P.V. Ritschl, L. Wiering, T. Dziodzio, M. Jara, J. Kruppa, U. Schoeneberg, N. Raschzok, F. Butz, B. Globke, P. Seika, M. Maurer, M. Biebl, W. Schöning, M. Schmelzle, I.M. Sauer, F. Tacke, R. Öllinger, J. Pratschke
Magnetic resonance elastography quantification of the solid-to-fluid transition of liver tissue due to decellularization
H. Everwien, A. Ariza de Schellenberger, N. Haep, H. Tzschätzsch, J. Pratschke, I.M. Sauer, J. Braun, K.H. Hillebrandt, I. Sack
Characterization of Pancreatic and Biliary Cancer Stem Cells in Patient-derived Tissue
J. Gogolok, E. Seidel, A. Strönisch, A. Reutzel-Selke, I.M. Sauer, J. Pratschke, M. Bahra, R.B. Schmuck
Hospitalization before liver transplantation predicts post-transplant patient survival - a propensity-score matched analysis
L. Wiering, R. Öllinger, J. Kruppa, U. Schoeneberg, T. Dziodzio, M. Jara, M. Biebl, R. Dargie, N. Raschzok, W. Schöning, D. Eurich, M. Schmelzle, I.M. Sauer, J. Pratschke, P.V. Ritschl
Tissue-based miRNA mapping in alcoholic liver cirrhosis: different profiles in cirrhosis with or without hepatocellular carcinoma
P. Felgendreff, N. Raschzok, K. Kunze, A. Leder, S. Lippert, S. Klunk, H.M. Tautenhahn, H.M. Hau, R.B. Schmuck, A. Reutzel-Selke, I.M. Sauer, M. Bartels, M.H. Morgül
Development of a rat liver machine perfusion system for normothermic and subnormothermic conditions
M. Nösser, J.M.G.V. Gassner, S. Moosburner, D. Wyrwal, F. Claussen, K.H. Hillebrandt, R. Horner, P. Tang, A. Reutzel-Selke, D. Polenz, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
Hepatocyte Transplantation to the Liver via the Splenic Artery in a Juvenile Large Animal Model
J. Siefert, K.H. Hillebrandt, S. Moosburner, P. Podrabsky, D. Geisel, T. Denecke, J.K. Unger, B. Sawitzki, S. Gül-Klein, S. Lippert, P. Tang, A. Reutzel-Selke, M.H. Morgul, A.W. Reske, S. Kafert-Kasting, W. Rüdinger, J. Oetvoes, J. Pratschke, I.M. Sauer, N. Raschzok
Teburu – Open source 3D printable bioreactor for tissue slices as dynamic three-dimensional cell culture models.
A. Daneshgar, P. Tang, C. Remde, M. Lommel, S. Moosburner, U. Kertzscher, O. Klein, M. Weinhart, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Macrosteatosis is a huge problem in liver transplantation – however, not the only one we face
S. Moosburner, I.M. Sauer, J.M.G.V, Gassner, C. Schleicher, D. Bösebeck, A. Rahmel, J. Pratschke, N. Raschzok
Strategies based on organ decellularization and recellularization
K.H. Hillebrandt, H. Everwien, N. Haep, E. Keshi, J. Pratschke, I.M. Sauer
Operieren im digitalen Raum – Mixed Reality in der Chirurgie [Operating within the digital space – mixed reality in surgery]
I.M. Sauer, M. Queisner, M. Pogorzhelskiy, J. Pratschke
Diagnostic Biomarkers to Diagnose Acute Allograft Rejection After Liver Transplantation: Systematic Review and Meta-Analysis of Diagnostic Accuracy Studies
F. Krenzien, E. Keshi, K. Splith, S. Griesel, K. Kamali, I.M. Sauer, L. Feldbrügge, J. Pratschke, A. Leder, M. Schmelzle
Immunologic cellular characteristics of the tumour microenvironment of hepatocellular carcinoma drive patient outcomes
G. Atanasov, K. Dino, K. Schierle, C. Dietel, G. Aust, J. Pratschke, D. Seehofer, M. Schmelzle, H.M. Hau
Impact of Percoll purification on isolation of primary human hepatocytes
R. Horner, J.G.M.V. Gassner, M. Kluge, P. Tang, S. Lippert, K.H. Hillebrandt, S. Moosburner, A. Reutzel-Selke, J. Pratschke, I.M. Sauer, N. Raschzok
First Healthy Baby After Deceased Donor Uterus Transplantation: Birth to a New Era?
M.M. Maurer, I.M. Sauer, J. Pratschke, S.G. Tullius
Human Stem Cells Promote Liver Regeneration After Partial Hepatectomy in BALB/C Nude Mice
S. Wabitsch, C. Benzing, F. Krenzien, K. Splith, P.K. Haber, A. Arnold, M. Nösser, C. Kamali, F. Hermann, C. Günther, D. Hirsch, I.M. Sauer, J. Pratschke, M. Schmelzle
Mixed and Augmented Reality – Why Surgeons Should Care
M. Queisner, J. Pratschke, I.M. Sauer
Composite tissue allotransplantation: opportunities and challenges
J. Iske, Y. Nian, R. Maenosono, M. Maurer, I.M. Sauer, S.G. Tullius
High donor age for liver transplantation : Tackling organ scarcity in Germany
S. Moosburner, P.V. Ritschl, L. Wiering, J.M.G.V. Gassner, R. Öllinger , J. Pratschke, i.M. Sauer, N. Raschzok
Liver Assist Systems for Bridging to Transplantation: Devices and Concepts
N. Raschzok, K.H. Hillebrandt, I.M. Sauer
Diffusion-weighted magnetic resonance imaging using a preclinical 1 T PET/MRI in healthy and tumor-bearing rats
J. Albrecht, D. Polenz, A.A. Kühl, J.M.M. Rogasch, A. Leder, I.M. Sauer, M. Babos, G. Mócsai, N. Beindorff, I.G. Steffen, W. Brenner, E.J. Koziolek
Minimally Invasive Liver Surgery in Elderly Patients-A Single-Center Experience
S. Wabitsch, P.K. Haber, N. Ekwelle, A. Kästner, F. Krenzien, C. Benzing, G. Atanasov, J.S. Bellingrath, G. Bauer, W. Schöning, R. Öllinger, J. Pratschke, M. Schmelzle
Improvement of normothermic ex vivo machine perfusion of rat liver grafts by dialysis and Kupffer Cell inhibition with glycine
J.M.G.V. Gassner, M. Nösser, S. Moosburner, R. Horner, P. Tang, L. Wegener, D. Wyrwal, F. Claussen, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
Real world usability analysis of two augmented reality headsets in visceral surgery.
S. Moosburner, C. Remde, P. Tang, M. Queisner, N. Haep, J. Pratschke, I.M. Sauer
Laparoscopic Resection for Adenocarcinoma of the Stomach or Gastroesophageal Junction Improves Postoperative Outcomes: a Propensity Score Matching Analysis
A. Andreou, S. Knitter, S. Chopra, C. Denecke, M. Schmelzle, B. Struecker, A.C. Heilmann, J. Spenke, T. Hofmann, P.C. Thuss-Patience, M. Bahra, J. Pratschke, M. Biebl
Prevalence of Steatosis Hepatis in the Eurotransplant Region: Impact on Graft Acceptance Rates
S. Moosburner, J.M.G.V. Gassner, M. Nösser, J. Pohl, D. Wyrwal, F. Claussen, P.V. Ritschl, D. Dragun, J. Pratschke, I.M. Sauer, N. Raschzok
The nanomolar sensing of nicotinamide adenine dinucleotide in human plasma using a cycling assay in albumin modified simulated body fluids
P. Brunnbauer, A. Leder, C. Kamali, K. Kamali, E. Keshi, K. Splith, S. Wabitsch, P. Haber, G. Atanasov, L. Feldbrügge, I.M. Sauer, J. Pratschke, M. Schmelzle, F. Krenzien
The Falciform Ligament for Mesenteric and Portal Vein Reconstruction in Local Advanced Pancreatic Tumor: A Surgical Guide and Single-Center Experience
T. Malinka, F. Klein, T. Denecke, U. Pelzer, J. Pratschke, M. Bahra
Mononuclear-cell-derived microparticles attenuate endothelial inflammation by transfer of miR-142-3p in a CD39 dependent manner
S. Kuhn, K. Splith, C. Ballschuh, L. Feldbrügge, F. Krenzien, G. Atanasov, C. Benzing, H.M. Hau, C. Engelmann, T. Berg, J. Schulte Am Esch, J. Pratschke, S.C. Robson, M. Schmelzle
Tumor-stromal cross-talk modulating the therapeutic response in pancreatic cancer
C.C.M. Neumann, E. von Hörschelmann, A. Reutzel-Selke, E. Seidel, I.M. Sauer, J. Pratschke, M. Bahra, R.B. Schmuck
Clinicopathological Stratification and Long-term Follow-up of Patients with Periampullary Carcinomas
R.B. Schmuck, C. Brokat, A. Andreou, M. Felsenstein, F. Klein, B. Sinn, J. Pratschke, M. Bahra
Strengths, Weaknesses, Opportunities, and Threats of Centralized Pancreatic Surgery: a Single-Center Analysis of 3000 Consecutive Pancreatic Resections
F. Klein, U. Pelzer, R.B. Schmuck, T. Malinka, M. Felsenstein, T. Denecke, J. Pratschke, M. Bahra
Validity of the Iwate criteria for patients with hepatocellular carcinoma undergoing minimally invasive liver resection
F. Krenzien, S. Wabitsch, P. Haber, C. Kamali, P. Brunnbauer, C. Benzing, G. Atanasov, G. Wakabayashi, R. Öllinger, J. Pratschke, M. Schmelzle
Angiogenic miRNAs, the angiopoietin axis and related TIE2-expressing monocytes affect outcomes in cholangiocarcinoma
G. Atanasov, C. Dietel, L. Feldbrügge, C. Benzing, F. Krenzien, A. Brandl, S. Katou, K. Schierle, S.C. Robson, K. Splith, G. Wiltberger, A. Reutzel-Selke, S. Jonas, A. Pascher, M. Bahra, J. Pratschke, M. Schmelzle
Routine portal vein resection for pancreatic adenocarcinoma shows no benefit in overall survival
F. Klein, F. Berresheim, M. Felsenstein, T. Malinka, U. Pelzer, T. Denecke, J. Pratschke, M. Bahra
Distal Pancreatectomy Combined with Multivisceral Resection Is Associated with Postoperative Complication Rates and Survival Comparable to Those After Standard Procedures
T. Malinka, F. Klein, A. Andreou, J. Pratschke, M. Bahra
The predictive value of the LiMax-test for the isolation of primary human hepatocytes
R.D. Major, M. Kluge, M. Jara, M. Nösser, R. Horner, J. Gassner, B. Struecker, P. Tang, S. Lippert, A. Reutzel-Selke, D. Geisel, T. Denecke, M. Stockmann, J. Pratschke, I.M. Sauer, N. Raschzok
Comparison of Single-Port Versus Standard Multiport Left Lateral Liver Sectionectomy
B. Struecker, P. Haber, R. Öllinger, M. Bahra, A. Pascher, J. Pratschke, M. Schmelzle
Liver Transplantation and Liver Resection for Cirrhotic Patients with Hepatocellular Carcinoma: Comparison of Long-Term Survivals
F. Krenzien, M. Schmelzle, B. Struecker, N. Raschzok, C. Benzing, M. Jara, M. Bahra, R. Öllinger, I.M. Sauer, A. Pascher, J. Pratschke, A. Andreou
Living-Donor Liver Transplant: An Analysis of Postoperative Outcome and Health-Related Quality of Life in Liver Donors
C. Benzing, M. Schmelzle, R. Oellinger, K. Gruettner, A.K. Muehlisch, N. Raschzok, I.M. Sauer, M. Bahra, J. Pratschke, S. Guel-Klein
This website or its third-party tools use cookies, which are necessary to its functioning and required to achieve the purpose illustrated in the Disclaimer. By closing this banner, scrolling this page, clicking a link or continuing to browse otherwise, you agree to the use of cookies.