Title - Change Me
2025
Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.
2025
2024
2023
2022
2021
2020
2019
2018
Evaluation of Anastomotic Leak after Esophagectomy for Esophageal Cancer:
Typical Time Point of Occurrence, Mode of Diagnosis, Value of Routine Radiocontrast Agent Studies and Therapeutic Options
B. Struecker, A. Andreou, S. Chopra, A.C. Heilmann, J. Spenke, C. Denecke, I.M. Sauer, M. Bahra, J. Pratschke, M. Biebl
2017
Incidence and Risk Factors of Symptomatic Hiatal Hernia Following Resection for Gastric and Esophageal Cancer
A. Andreou, S. Pesthy, B. Struecker, M. Dadras, J. Raakow, S. Knitter, G. Duwe, I.M. Sauer, A.S. Beierle, C. Denecke, S. Chopra, J. Pratschke, M. Biebl
Plasma expansion is key for sustained liver function and viability during normothermic and subnormothermic ex vivo machine perfusion in a rat model
J.M.G.V. Gassner, M. Nösser, R. Horner, K.H. Hillebrandt, S. Moosburner, L. Wegener, P. Demko, R. Arsenic, B. Struecker, J. Pratschke, I.M. Sauer, N. Raschzok
Mixed Reality in visceral surgery – development of a suitable workflow and evaluation of intraoperative use-cases
I.M. Sauer, M. Queisner, P. Tang, S. Moosburner, O. Hoepfner, R. Horner, R. Lohmann, J. Pratschke
The magnetic field of magnetic resonance imaging systems does not affect cells labeled with micrometer-sized iron oxide particles
M. Kluge, A. Leder, K.H. Hillebrandt, B. Struecker, D. Geisel, T. Denecke, R.D. Major, A. Reutzel-Selke, P. Tang, S. Lippert, Ch. Schmidt, J. Pratschke, I.M. Sauer, N. Raschzok
Computed tomography-based survey of the vascular anatomy of the juvenile Göttingen minipig
J. Siefert, K.H. Hillebrandt, M. Kluge, D. Geisel, P. Podrabsky, T. Denecke, M. Nösser, J. Gassner, A. Reutzel-Selke, B. Strücker, M.H. Morgul, S. Guel-Klein, J.K. Unger, A. Reske, J. Pratschke, I.M. Sauer, N. Raschzok
Isolation, characterization and cold storage of cells isolated from diseased explanted livers
E. Belaschk, S. Rohn, R. Mukiibi, A. Reutzel-Selke, P. Tang, B. Sawitzki, J. Pratschke, I.M. Sauer, M.T. Mogl
Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans
H. Napierala, K. Hillebrandt, N. Haep, P. Tang, M. Tintemann, J. Gassner, M. Noesser, H. Everwien, N. Seiffert, M. Kluge, E. Teegen, D. Polenz, S. Lippert, D. Geisel, A. Reutzel-Selke, N. Raschzok, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker
The value of microparticles in detecting acute rejection episodes after liver transplantation
M.H. Morgul, K. Splith, C. Leonhardt, N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, A. Andreou, C. Atanasov, C. Benzing, F. Krenzien, H.M. Hau, P. Felgendreff, S. Klunk, J. Pratschke, I.M. Sauer, M. Schmelzle
Bovine serum albumine-glutaraldehyde sealed fish-mouth closure of the pancreatic remnant during distal pancreatectomy
F. Klein, I.M. Sauer, J. Pratschke, M. Bahra
The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism
C. von Loeffelholz, S. Lieske, F. Neuschäfer-Rube, D.M. Willmes, N. Raschzok , I.M. Sauer, J. König, M. Fromm, P. Horn, A. Chatzigeorgiou, A. Pathe-Neuschäfer-Rube, J. Jordan, A.F. Pfeiffer, C. Mingrone, S.R. Bornstein, P. Stroehle, C. Harms, F.T. Wunderlich, S.L. Helfand , M. Bernier, R. de Cabo, G.I. Shulman, T. Chavakis, G.P. Püschel, A.L. Birkenfeld
Bile: miRNA pattern and protein based biomarkers may predict acute cellular rejection after liver transplantation
R.B. Schmuck, A. Reutzel-Selke, N. Raschzok, M.H. Morgul, B. Struecker, S. Lippert, C. de Carvalho Fischer, M. Schmelzle, S. Boas-Knoop, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer
Hepatotoxicity following systemic therapy for colorectal liver metastases and the impact of chemotherapy-associated liver injury on outcomes after curative liver resection
G. Duwe, S. Knitter, S. Pesthy, A.S. Beierle, M. Bahra, M. Schmelzle, R.B. Schmuck, P. Lohneis, N. Raschzok, R. Öllinger, M. Sinn, B. Struecker, I.M. Sauer, J. Pratschke, A. Andreou
New technique for obesity surgery: internal gastric plication technique using intragastric single-port (IGS-IGP) in an experimental model
V. Müller, P. Fikatas, S. Gül, M. Noesser, K.T. Fuehrer, I. Sauer, J. Pratschke, R. Zorron
Routine radiologic contrast agent examination after gastrectomy for gastric cancer is not useful
B. Struecker, S. Chopra, A.C. Heilmann, J. Spenke, C. Denecke, I.M. Sauer, M. Bahra, J. Pratschke, A. Andreou, M. Biebl
Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions
B. Struecker, A. Butter, K. Hillebrandt, D. Polenz , A. Reutzel-Selke, P. Tang, S. Lippert, A. Leder, S. Rohn, D. Geisel, T. Denecke, K. Aliyev, K. Jöhrens, N. Raschzok, P. Neuhaus, J. Pratschke, I.M. Sauer
2016
Evolution of graft morphology and function after recellularization of decellularized rat livers
A. Butter, K. Aliyev, K.-H. Hillebrandt, N. Raschzok, M. Kluge, N. Seiffert, P. Tang, H. Napierala, M.I. Ashraf, A. Reutzel-Selke, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker
The impact of tumor cell proliferation on occult micrometastases, tumor recurrence and patient outcome following resection for liver malignancies
A. Andreou, M. Schmelzle, I.M. Sauer, M. Bahra, J. Pratschke
Hepatocyte isolation after laparoscopic liver resection
R. Horner*, M. Kluge*, R.M. Major, A. Reutzel-Selke, J. Gassner, M. Nösser, B. Strücker, M.H. Morgül, J. Pratschke, I.M. Sauer, N. Raschzok
Allogeneic liver transplantation and subsequent syngeneic hepatocyte transplantation in a rat model – proof of concept for in vivo tissue engineering
S. Rohn, J. Schroeder, H. Riedel, D. Polenz, K. Stanko, A. Reutzel-Selke, P. Tang, L. Brusendorf, N. Raschzok, P. Neuhaus, J. Pratschke, B. Sawitzki, I.M. Sauer, M.T. Mogl
microRNA signatures in peripheral blood fail to detect acute cellular rejection after liver transplantation
N. Raschzok, A. Reutzel-Selke, R. Schmuck, L. Tannus, M. Morgul, C. Dietel, A. Leder, B. Struecker, S. Lippert, H. Sallmon, M. Schmelzle, M. Bartels, S. Jonas, J. Pratschke, I.M. Sauer
Single Pass Albumin Dialysis (SPAD) – A dose finding study to define optimal albumin concentration and dialysate flow
R.B. Schmuck, G.-H. Nawrot, P. Fikatas, A. Reutzel-Selke, J. Pratschke, I.M. Sauer
Human hepatocyte isolation: Does portal vein embolization affect the outcome?
M. Kluge, A. Reutzel-Selke, H. Napierala, K.H. Hillebrandt, R.D. Major, B. Struecker, A. Leder, J. Siefert, P. Tang, S. Lippert, D. Seehofer, J. Pratschke, I.M. Sauer, N. Raschzok
Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver
C. von Loeffelholz, S. Döcke, J.F. Lock, S. Lieske, P. Horn, J. Kriebel, S. Wahl, P. Singmann, T. de Las Heras Gala, H. Grallert, N. Raschzok, I.M. Sauer, R. Heller, G. Jahreis, R.A. Claus, M. Bauer, M. Stockmann, A.L. Birkenfeld, A.F. Pfeiffer
Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue – A statistical model based on stepwise penalized logistic regression
M.H. Morgul, S. Klunk, Z. Anastasiadou, U. Gauger, C. Dietel, A. Reutzel-Selke, P. Felgendref, H.M. Hau, H.M. Tautenhahn, R.B. Schmuck, N. Raschzok, I.M. Sauer, M. Bartels
Predictive factors for extrahepatic recurrence of hepatocellular carcinoma following liver transplantation
A. Andreou, M. Bahra, M. Schmelzle, R. Öllinger, R. Sucher, I.M. Sauer, S. Guel-Klein, B. Struecker, D. Eurich, F. Klein, A. Pascher, J. Pratschke, D. Seehofer
Risk factors for bile leakage after hepatectomy
B. Struecker, A. Andreou, I.M. Sauer, J. Pratschke, D. Seehofer
Implantation of a tissue engineered Neo Bile Duct in domestic pigs
B. Struecker, K. Hillebrandt, N. Raschzok, K. Jöhrens, A. Butter, P. Tang, A. Andreou, H. Napierala, D. Polenz, A. Reutzel-Selke, T. Denecke, J. Pratschke, I.M Sauer
The impact of directly acting antivirals on the enzymatic liver function of liver transplant recipients with recurrent hepatitis C
N. Raschzok, E. Schott, A. Reutzel-Selke, I. Damrah, S. Gül-Klein, B. Strücker, I.M. Sauer, J. Pratschke, D. Eurich, M. Stockmann
The Impact of Obesity on Outcomes Following Resection for Gastric Cancer
B. Struecker, M. Biebl, M. Dadras, S. Chopra, C. Denecke, J. Spenke, A.C. Heilmann, M. Bahra, I.M. Sauer, J. Pratschke, A. Andreou
Acute graft dysfunction 17 years after liver transplant: A challenging clinical and histologic manifestation of hepatitis E
K.H. Hillebrandt, R. Arsenic, J. Hofmann, D. Eurich, S. Gül, B. Strücker, I.M. Sauer, J. Pratschke, M. Stockmann, N. Raschzok
Anastomotic leak predicts diminished long-term survival after resection for gastric and esophageal cancer
A. Andreou, M. Biebl, M. Dadras, B. Struecker, I.M. Sauer, P.C. Thuss-Patience, S. Chopra, P. Fikatas, M. Bahra, D. Seehofer, J. Pratschke, S.C. Schmidt
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
Noll EM, Eisen C, Stenzinger A, Espinet E, Muckenhuber A, Klein C, Vogel V, Klaus B, Nadler W, Rösli C, Lutz C, Kulke M, Engelhardt J, Zickgraf FM, Espinosa O, Schlesner M, Jiang X, Kopp-Schneider A, Neuhaus P, Bahra M, Sinn BV, Eils R, Giese NA, Hackert T, Strobel O, Werner J, Büchler MW, Weichert W, Trumpp A, Sprick MR.
Predictive factors for extrahepatic recurrence of hepatocellular carcinoma following orthotopic liver transplantation
Andreou A, Bahra M, Schmelzle M, Sucher R, Sauer IM, Guel-Klein S, Struecker B, Eurich D, Klein F, Pascher A, Pratschke J, Seehofer D.
Perioperative treatment options in resectable pancreatic cancer - how to improve long-term survival
Sinn M, Bahra M, Denecke T, Travis S, Pelzer U, Riess H.
P53 overexpression and Ki67-index are associated with outcome in ductal pancreatic adenocarcinoma with adjuvant gemcitabine treatment
Striefler JK, Sinn M, Pelzer U, Jühling A, Wislocka L, Bahra M, Sinn BV, Denkert C, Dörken B, Oettle H, Riess H, Bläker H, Lohneis P.
Long-term Survival After Surgical Treatment of Renal Cell Carcinoma Metastasis Within the Pancreas
Fikatas P, Klein F, Andreou A, Schmuck RB, Pratschke J, Bahra M.
Distal bile duct carcinomas and pancreatic ductal adenocarcinomas: postulating a commor tumor entity
Schmuck RB, de Carvalho Fischer CV, Neumann C, Pratschke J, Bahra M
Pancreatogastrostomy Versus Pancreatojejunostomy for RECOnstruction After PANCreatoduodenectomy (RECOPANC, DRKS 00000767): Perioperative and Long-term Results of a Multicenter Randomized Controlled Trial
Keck T, Wellner UF, Bahra M, Klein F, Sick O, Niedergethmann M, Wilhelm TJ, Farkas SA, Börner T, Bruns C, Kleespies A, Kleeff J, Mihaljevic AL, Uhl W, Chromik A, Fendrich V, Heeger K, Padberg W, Hecker A, Neumann UP, Junge K, Kalff JC, Glowka TR, Werner J, Knebel P, Piso P, Mayr M, Izbicki J, Vashist Y, Bronsert P, Bruckner T, Limprecht R, Diener MK, Rossion I, Wegener I, Hopt UT.
2015
microRNAs in liver tissue engineering – new promises for failing organs
N. Raschzok, H. Sallmon, J. Pratschke, I.M. Sauer
Human equilibrative nucleoside transporter 1 expression analysed by the clone SP 120 rabbit antibody is not predictive in patients with pancreatic cancer treated with adjuvant gemcitabine - Results from the CONKO-001 trial
Sinn M, Riess H, Sinn BV, Stieler JM, Pelzer U, Striefler JK, Oettle H, Bahra M, Denkert C, Bläker H, Lohneis P.
Ataxia-telangiectasia-mutated protein kinase levels stratify patients with pancreatic adenocarcinoma into prognostic subgroups with loss being a strong indicator of poor survival
Kamphues C, Bova R, Bahra M, Klauschen F, Muckenhuber A, Sinn BV, Warth A, Goeppert B, Endris V, Neuhaus P, Weichert W, Stenzinger A.
Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay
Arnold A, Bahra M, Lenze D, Bradtmöller M, Guse K, Gehlhaar C, Bläker H, Heppner FL, Koch A.
The DNA index as a prognostic tool in hilar cholangiocarcinoma
Kamphues C, Al-Abadi N, Bova R, Rademacher S, Al-Abadi H, Klauschen F, Bahra M, Neuhaus P, Pratschke J, Seehofer D.
Prognostic significance of DNA cytometry for adjuvant therapy response in pancreatic cancer
Klein F, Bahra M, Schirmeier A, Al-Abadi H, Pratschke J, Pelzer U, Oettle H, Striefler J, Riess H, Sinn M.
Implications of imaging criteria for the management and treatment of intraductal papillary mucinous neoplasms - benign versus malignant findings
Walter TC, Steffen IG, Stelter LH, Maurer MH, Bahra M, Faber W, Klein F, Bläker H, Hamm B, Denecke T, Grieser C.
Cytoreductive Surgery for Pancreatic Cancer improves Overall Outcome of Gemcitabine-Based Chemotherapy
Bahra M, Pratschke J, Klein F, Neuhaus P, Boas-Knoop S, Puhl G, Denecke T, Pullankavumkal JR, Sinn M, Riess H, Pelzer U.
CT and MRI Findings of Autoimmune Polymorph Bifocal Pancreatitis Mimicking Pancreatic Adenocarcinoma: A Case Report and Review of the Literature
Rotzinger R, Bläker H, Bahra M, Denecke T, Grieser C.
Patient and tumor biology predict survival beyond the Milan criteria in liver transplantation for hepatocellular carcinoma.
Andreou A, Gül S, Pascher A, Schöning W, Al-Abadi H, Bahra M, Klein F, Denecke T, Strücker B, Puhl G, Neuhaus P, Pratschke J, Seehofer D.
Tumor DNA-index and α-fetoprotein level define outcome following liver transplantation for advanced hepatocellular carcinoma.
Andreou A, Bahra M, Guel S, Struecker B, Sauer IM, Klein F, Pascher A, Pratschke J, Seehofer D.
Procedure for Decellularization of Rat Livers in an Oscillating-pressure Perfusion Device
K. Hillebrandt, D. Polenz, A. Butter, P. Tang, A. Reutzel-Selke, A. Andreou, H. Napierala, N. Raschzok, J. Pratschke, I.M. Sauer, B. Struecker
CD44 and CXCL9 serum protein levels predict the risk of clinically significant allograft rejection after liver transplantation
N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, M.H. Morgul, U. Gauger,K.A. Prabowo, L.-M. Tannus, A. Leder, B. Struecker, S. Boas-Knoop, M. Bartels, S. Jonas, Ch. Lojewski, G. Puhl, D. Seehofer, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer
Tissue Engineered Grafts – 160 Years After R. Virchow's Omnis Cellula e Cellula
I.M. Sauer
Micron-sized iron oxide-containing particles for microRNA-targeted manipulation and MRI-based tracking of transplanted cells
A. Leder*, N. Raschzok*, C. Schmidt, D. Arabacioglu, A. Butter, S. Kolano, L.S. de Sousa Lisboa, W. Werner, D. Polenz, A. Reutzel-Selke, J. Pratschke, I.M. Sauer
2014
Liver support strategies: cutting-edge technologies
B. Struecker, N. Raschzok, I.M. Sauer
Response to preoperative chemotherapy predicts survival in patients undergoing hepatectomy for liver metastases from gastric and esophageal cancer
Andreou A, Viganò L, Zimmitti G, Seehofer D, Dreyer M, Pascher A, Bahra M, Schoening W, Schmitz V, Thuss-Patience PC, Denecke T, Puhl G, Vauthey JN, Neuhaus P, Capussotti L, Pratschke J, Schmidt SC.
Intensity-modulated and image-guided radiotherapy in patients with locally advanced inoperable pancreatic cancer after preradiation chemotherapy
Sinn M, Ganeshan R, Graf R, Pelzer U, Stieler JM, Striefler JK, Bahra M, Wust P, Riess H.
DNA index is a strong predictive marker in intrahepatic cholangiocarcinoma: the results of a five-year prospective study
Kamphues C, Al-Abadi N, Dürr A, Bova R, Klauschen F, Stenzinger A, Bahra M, Al-Abadi H, Neuhaus P, Seehofer D.
Hedgehog pathway as a potential treatment target in human cholangiocarcinoma
D. Riedlinger, M. Bahra, S. Boas-Knoop, S. Lippert, M. Bradtmöller, K. Guse, D. Seehofer, R. Bova, I.M. Sauer, P. Neuhaus, A. Koch, C. Kamphues
Porcine liver decellularization under oscillating pressure conditions – A technical refinement to improve the homogeneity of the decellularization process
B. Struecker, K. Hillebrandt, R. Voitl, A. Butter, R.B. Schmuck, A. Reutzel-Selke, D. Geisel, K. Joehrens, P.A. Pickerodt, N. Raschzok, G. Puhl, P. Neuhaus, J. Pratschke, I.M. Sauer
Independent Effects of Sham Laparotomy and Anesthesia on Hepatic microRNA Expression in Rats
W. Werner, H. Sallmon, A. Leder, S. Lippert, A. Reutzel-Selke, M.H. Morgül, S. Jonas, S. Dame, P. Neuhaus, J. Iacomini, S.G. Tullius, I.M. Sauer, N. Raschzok
Significant impact of patient age on outcome after liver resection for HCC in cirrhosis
Faber W, Stockmann M, Schirmer C, Möllerarnd A, Denecke T, Bahra M, Klein F, Schott E, Neuhaus P, Seehofer D.
Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial
Pelzer U, Hilbig A, Stieler JM, Bahra M, Sinn M, Gebauer B, Dörken B, RiessPelzer U, Hilbig A, Stieler JM, Bahra M, Sinn M, Gebauer B, Dörken B, Riess
Radiologic resectability assessment in pancreatic cancer
Denecke T, Grieser C, Neuhaus P, Bahra M.
Hedgehog pathway as a potential treatment target in human cholangiocarcinoma
Riedlinger D, Bahra M, Boas-Knoop S, Lippert S, Bradtmöller M, Guse K, Seehofer D, Bova R, Sauer IM, Neuhaus P, Koch A, Kamphues C.
KRAS mutations in codon 12 or 13 are associated with worse prognosis in pancreatic ductal adenocarcinoma
Sinn BV, Striefler JK, Rudl MA, Lehmann A, Bahra M, Denkert C, Sinn M, Stieler J, Klauschen F, Budczies J, Weichert W, Stenzinger A, Kamphues C, Dietel M, Riess H.
Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas
Riener MO, Thiesler T, Hellerbrand C, Amann T, Cathomas G, Fritzsche FR, Dahl E, Bahra M, Weichert W, Terracciano L, Kristiansen G.
α-Smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study
Sinn M, Denkert C, Striefler JK, Pelzer U, Stieler JM, Bahra M, Lohneis P, Dörken B, Oettle H, Riess H, Sinn BV.
Prognostic factors for long-term survival in patients with ampullary carcinoma: the results of a 15-year observation period after pancreaticoduodenectomy
Klein F, Jacob D, Bahra M, Pelzer U, Puhl G, Krannich A, Andreou A, Gül S, Guckelberger O.
Axon Guidance Factor SLIT2 Inhibits Neural Invasion and Metastasis in Pancreatic Cancer
Göhrig A, Detjen KM, Hilfenhaus G, Körner JL, Welzel M, Arsenic R, Schmuck R, Bahra M, Wu JY, Wiedenmann B, Fischer C.
RAS Mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases
Mise Y, Zimmitti G, Shindoh J, Kopetz S, Loyer EM, Andreou A, Cooper AB, Kaur H, Aloia TA, Maru DM, Vauthey JN.
Residual tumor thickness at the tumor-normal tissue interface predicts the recurrence-free survival in patients with liver metastasis of breast cancer
Zhou JH, Rosen D, Andreou A, Brouquet A, Abbott D, Loyer E, Gonzalez-Angulo AM, Kopetz S, Meric-Bernstam F, Kuerer H, Abdalla E, Vauthey JN, Sahin AA, Maru DM.
2013
Functionalizable silica-based micron-sized iron oxide particles for cellular Magnetic Resonance Imaging
N. Raschzok, C.M. Langer, Ch. Schmidt, K.H. Lerche, N. Billecke, K. Nehls, N.B. Schlüter, A. Leder, S. Rohn, M.T. Mogl, L. Lüdemann, L. Stelter, U.K. Teichgräber, P. Neuhaus, I.M. Sauer
Value of carbohydrate antigen 19-9 in predicting response and therapy control in patients with metastatic pancreatic cancer undergoing first-line therapy
Pelzer U, Hilbig A, Sinn M, Stieler J, Bahra M, Dörken B, Riess H.
Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy
Andreou A, Aloia TA, Brouquet A, Dickson PV, Zimmitti G, Maru DM, Kopetz S, Loyer EM, Curley SA, Abdalla EK, Vauthey JN.
Blood group determinates incidence for pancreatic cancer in Germany
Pelzer U, Klein F, Bahra M, Sinn M, Dörken B, Neuhaus P, Meyer O, Riess H.
From the International Cooperative Study Group on Hepatocellular Carcinoma. Improved long-term survival after major resection for hepatocellular carcinoma: a multicenter analysis based on a new definition of major hepatectomy
Andreou A, Vauthey JN, Cherqui D, Zimmitti G, Ribero D, Truty MJ, Wei SH, Curley SA, Laurent A, Poon RT, Belghiti J, Nagorney DM, Aloia TA.
Identification of a novel human polyomavirus in organs of the gastrointestinal tract
Korup S, Rietscher J, Calvignac-Spencer S, Trusch F, Hofmann J, Moens U, Sauer I, Voigt S, Schmuck R, Ehlers B.
Does long-term survival in patients with pancreatic cancer really exist? Results from the CONKO-001 study
Sinn M, Striefler JK, Sinn BV, Sallmon D, Bischoff S, Stieler JM, Pelzer U, Bahra M, Neuhaus P, Dörken B, Denkert C, Riess H, Oettle H.
The impact of simultaneous liver resection for occult liver metastases of pancreatic adenocarcinoma
Klein F, Puhl G, Guckelberger O, Pelzer U, Pullankavumkal JR, Guel S, Neuhaus P, Bahra M.
Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging
Grieser C, Heine G, Stelter L, Steffen IG, Rothe JH, Walter TC, Fischer C, Bahra M, Denecke T.
Long-term results of liver resection for hepatocellular carcinoma in noncirrhotic liver
Faber W, Sharafi S, Stockmann M, Denecke T, Sinn B, Puhl G, Bahra M, Malinowski MB, Neuhaus P, Seehofer D.
Greater complexity of liver surgery is not associated with an increased incidence of liver-related complications except for bile leak: an experience with 2,628 consecutive resections
Zimmitti G, Roses RE, Andreou A, Shindoh J, Curley SA, Aloia TA, Vauthey JN.
RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases
Vauthey JN, Zimmitti G, Kopetz SE, Shindoh J, Chen SS, Andreou A, Curley SA, Aloia TA, Maru DM.
Methods to improve resectability of hepatocellular carcinoma
Brouquet A, Andreou A, Shindoh J, Vauthey JN.
APACHE III score is superior to King's College Hospital criteria, MELD score and APACHE II score to predict outcomes after liver transplantation for acute liver failure
P. Fikatas, J.E. Lee, I.M. Sauer, S.C. Schmidt, D. Seehofer, G. Puhl, O. Guckelberger
Survival without biliary complications after liver transplant for primary sclerosing cholangitis
M.T. Mogl, K. Albert, A. Pascher, I. Sauer, G. Puhl, S. Gül, C. Schönemann, P. Neuhaus, O. Guckelberger
Elevated hepatic chemerin gene expression in progressed human non-alcoholic fatty liver disease
S. Döcke, J.F. Lock, A.L. Birkenfeld, S. Hoppe, S. Lieske, A. Rieger, N. Raschzok, I.M. Sauer, S. Florian, M.A. Osterhoff, R. Heller, K. Herrmann, S. Lindenmüller, P. Horn, M. Bauer, M.O. Weickert, P. Neuhaus, M. Stockmann, M. Möhlig, A.Fh. Pfeiffer C. von Loeffelholz
Evaluation of Arginine deiminase treatment in melanoma xenografts using 18F-FLT PET
S. Döcke, J.F. Lock, A.L. Birkenfeld, S. Hoppe, S. Lieske, A. Rieger, N. Raschzok, I.M. Sauer, S. Florian, M.A. Osterhoff, R. Heller, K. Herrmann, S. Lindenmüller, P. Horn, M. Bauer, M.O. Weickert, P. Neuhaus, M. Stockmann, M. Möhlig, A.Fh. Pfeiffer C. von Loeffelholz
Noninvasive monitoring of liver cell transplantation
N. Raschzok, H.M. Morgül, L. Stelter, I.M. Sauer
Effects of moderate and deep hypothermia on RNA-binding proteins RBM3 and CIRP expressions in murine hippocampal brain slices
G. Tong, S. Endersfelder, L.M. Rosenthal, S. Wollersheim, I.M. Sauer, C. Bührer, F. Berger, K.R. Schmitt
Identification of a novel human polyomavirus in organs of the gastrointestinal tract
S. Korup, J. Rietscher, S. Calvignac-Spencer, F. Trusch, J. Hofmann, U. Moens, I. Sauer, S. Voigt, R. Schmuck, B. Ehlers
2012
Feasibility of fast dynamic MRI for non-invasive monitoring during ectopic liver cell transplantation to the spleen in a porcine model
N. Raschzok, J. Pinkernelle, N. Billecke, K. Nehls, M. Powerski, I.M. Sauer, U. Teichgraber
A novel cannulation technique for isolation of human hepatocytes from explanted, diseased whole livers
D.C. Kehr, N. Raschzok, I.M. Sauer
Adjuvant chemotherapy with FOLFOX for primary colorectal cancer is associated with increased somatic gene mutations and inferior survival in patients undergoing hepatectomy for metachronous liver metastases
Andreou A, Kopetz S, Maru DM, Chen SS, Zimmitti G, Brouquet A, Shindoh J, Curley SA, Garrett C, Overman MJ, Aloia TA, Vauthey JN.
Linker-free recombinant human β2-defensin fusion proteins to validate defensin structure and function in small tissue samples
Andreou A, Coordes A, Erben U, Stroh T, Blunert K, Slavova N, Buhr H-J, Siegmund B, Kroesen A.J.
Liver resection for liver metastases from nondigestive endocrine cancer: extrahepatic disease burden defines outcome
Andreou A, Brouquet A, Bharathy KGS, Perrier ND, Abdalla EK, Curley SA, Glanemann M, Seehofer D, Neuhaus P, Vauthey JN, Aloia TA.
DNA Index as a Strong Prognostic Factor in Patients with Adenocarcinoma of the Pancreatic Head: Results of a 5-Year Prospective Study
Kamphues C, Al-Abadi H, Dürr A, Al-Abadi N, Schricke D, Bova R, Müller V, Stenzinger A, Klauschen F, Seehofer D, Neuhaus P, Bahra M.
Prolyl hydroxylase domain 2 protein is a strong prognostic marker in human gastric cancer
Kamphues C, Wittschieber D, Klauschen F, Kasajima A, Dietel M, Schmidt SC, Glanemann M, Bahra M, Neuhaus P, Weichert W, Stenzinger A.
Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas
Bahra M, Kamphues C, Boas-Knoop S, Lippert S, Esendik U, Schüller U, Hartmann W, Waha A, Neuhaus P, Heppner F, Pietsch T, Koch A.
Postoperative complications deteriorate long-term outcome in pancreatic cancer patients
Kamphues C, Bova R, Schricke D, Hippler-Benscheidt M, Klauschen F, Stenzinger A, Seehofer D, Glanemann M, Neuhaus P, Bahra M.
Role of IL28B polymorphism in the development of hepatitis C virus-induced hepatocellular carcinoma, graft fibrosis, and posttransplant antiviral therapy
Eurich D, Boas-Knoop S, Bahra M, Neuhaus R, Somasundaram R, Neuhaus P, Neumann U, Seehofer D.
High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer
Klauschen F, von Winterfeld M, Stenzinger A, Sinn BV, Budczies J, Kamphues C, Bahra M, Wittschieber D, Weichert W, Striefler J, Riess H, Dietel M, Denkert C.
Preliminary experience with CT-guided high-dose rate brachytherapy as an alternative treatment for hepatic recurrence of cholangiocarcinoma
Kamphues C, Seehofer D, Collettini F, Bahra M, Neuhaus P, Wust P, Denecke T, Gebauer B, Schnapauff D.
Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes
Winter C, Kristiansen G, Kersting S, Roy J, Aust D, Knösel T, Rümmele P, Jahnke B, Hentrich V, Rückert F, Niedergethmann M, Weichert W, Bahra M, Schlitt HJ, Settmacher U, Friess H, Büchler M, Saeger HD, Schroeder M, Pilarsky C, Grützmann R.
Matched-pair analysis of postoperative morbidity and mortality for pancreaticogastrostomy and pancreaticojejunostomy using mattress sutures in soft pancreatic tissue remnants
Klein F, Bahra M, Glanemann M, Faber W, Warnick P, Andreou A, Gül S, Jacob D.
Pancreatoenteral anastomosis or direct closure of the pancreatic remnant after a distal pancreatectomy: a single-centre experience
Klein F, Glanemann M, Faber W, Gül S, Neuhaus P, Bahra M.
KRAS mutation in colorectal cancer metastases after adjuvant FOLFOX for the primary
Vauthey JN, Kopetz S, Aloia TA, Andreou A.
Microvascular invasion does not predict long-term survival in hepatocellular carcinoma up to 2 cm: reappraisal of the staging system for solitary tumors
Shindoh J, Andreou A, Aloia TA, Zimmitti G, Lauwers GY, Laurent A, Nagorney DM, Belghiti J, Cherqui D, Poon RT, Kokudo N, Vauthey JN.
Liver regeneration after partial hepatectomy: inconsistent results of expression screenings for human, mouse, and rat miRNAs
N. Raschzok, H. Sallmon, C. Dame, I.M. Sauer
An operational concept for long-term cinemicrography of cells in mono- and co-culture under highly controlled conditions - the SlideObserver
N. Billecke, N. Raschzok, S. Rohn, M.H. Morgul, R. Schwartlander, M. Mogl, S. Wollersheim, K.R. Schmitt*, I.M. Sauer*
Improvement of the cold storage of isolated human hepatocytes
G. Pless, I.M. Sauer, U. Rauen
2011
Temporal expression profiles indicate a primary function for microRNA during the peak of DNA replication after rat partial hepatectomy
N. Raschzok, W. Werner, H. Sallmon, N. Billecke, C. Dame, P. Neuhaus, I.M. Sauer
Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate
Andreou A, Brouquet A, Abdalla EK, Aloia TA, Curley SA, Vauthey JN.
Distal pancreatectomy with en bloc resection of the celiac trunk for extended pancreatic tumor disease: an interdisciplinary approach
Andreou A, Denecke T, Podrabsky P, Grieser C, Warnick P, Bahra M, Klein F, Hamm B, Neuhaus P, Glanemann M.
Recent advances in the curative treatment of colorectal liver metastases.
Andreou A, Aloia TA, Brouquet A, Vauthey JN.
Recent advances in the curative treatment of colorectal liver metastases.
Andreou A, Aloia TA, Brouquet A, Vauthey JN.
Distal pancreatectomy with en bloc resection of the celiac trunk for extended pancreatic tumor disease: an interdisciplinary approach
Denecke T, Andreou A, Podrabsky P, Grieser C, Warnick P, Bahra M, Klein F, Hamm B, Neuhaus P, Glanemann M.
Genotypic and phenotypic characterization of side population of gastric cancer cell lines
Schmuck R, Warneke V, Behrens HM, Simon E, Weichert W, Röcken.
Safety of pancreatic surgery in patients with simultaneous liver cirrhosis: a single center experience
Warnick P, Mai I, Klein F, Andreou A, Bahra M, Neuhaus P, Glanemann M.
High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome
Brouquet A, Abdalla EK, Kopetz S, Garrett CR, Overman MJ, Eng C, Andreou A, Loyer EM, Madoff DC, Curley SA, Vauthey JN.
Recent advances in the curative treatment of colorectal liver metastases.
Andreou A, Aloia TA, Brouquet A, Vauthey JN.
Second-look operation in pancreatic carcinoma previously assessed as unresectable
Warnick P, Bahra M, Andreou A, Neuhaus P, Glanemann M.
Repeated liver resection for recurrent hepatocellular carcinoma
Faber W, Seehofer D, Neuhaus P, Stockmann M, Denecke T, Kalmuk S, Warnick P, Bahra M.
Association of mannose-binding lectin-2 gene polymorphism with the development of hepatitis C-induced hepatocellular carcinoma
Eurich D, Boas-Knoop S, Morawietz L, Neuhaus R, Somasundaram R, Ruehl M, Neumann UP, Neuhaus P, Bahra M, Seehofer D.
Labelling of primary human hepatocytes with micron-sized iron oxide particles in suspension culture suitable for large-scale preparation
N.N. Kammer, N. Billecke, M.H. Morgul, M.K. Adonopoulou, M. Mogl, M.D. Huang, S. Florek, K.R.L. Schmitt, N. Raschzok, I.M. Sauer
CARS microscopy for the visualization of micrometer-sized iron oxide MRI contrast agents in living cells
G. Rago, C.M. Langer, C. Brackman, J.P. Day, K.F. Domke, N. Raschzok, C. Schmidt, I.M. Sauer, A. Enejder, M.T. Mogl, M. Bonn
The APACHE III score as preoperative indicator of patient outcome in liver transplantation after fulminant hepatic failure
P. Fikatas, F. Ulrich, J.E. Lee, I.M. Sauer, S. Chopra, S.C. Schmidt, A. Pascher, J. Pratschke
In vitro evaluation of magnetic resonance imaging contrast agents for labeling human liver cells: implications for clinical translation
N. Raschzok, D.A. Muecke, M.K. Adonopoulou, N. Billecke, W. Werner, N.N. Kammer, A. Zielinski, P.A. Behringer, F. Ringel, M.D. Huang, P. Neuhaus, U. Teichgräber, I.M. Sauer
Continuous veno-venous single-pass albumin hemodiafiltration in children with acute liver failure
H. Ringe, V. Varnholt, M. Zimmering, W. Luck, A. Gratopp, K. König, S. Reich, I.M. Sauer, G. Gaedicke, U. Querfeld
2010
Monitoring of liver cell transplantation in a preclinical swine model using Magnetic Resonance Imaging
N. Raschzok, U. Teichgräber, N. Billecke, A. Zielinski, K. Steinz, N.N. Kammer, M.H. Morgul, S. Schmeisser, M.K. Adonopoulou, L. Morawietz, B. Hiebl, R. Schwartlander, W. Rüdinger, B. Hamm, P. Neuhaus, I.M. Sauer
Pancreas: Is there still a role for total pancreatectomy?
Bahra M, Neuhaus P.
Primary radical surgery in elderly patients with epithelial ovarian cancer: analysis of surgical outcome and long-term survival
Fotopoulou C, Savvatis K, Steinhagen-Thiessen E, Bahra M, Lichtenegger W, Sehouli J.
Second-look operation in pancreatic carcinoma previously assessed as unresectable
Warnick P, Bahra M, Andreou A, Neuhaus P, Glanemann M.
Preoperative multidetector row computed tomography for evaluation and assessment of resection criteria in patients with pancreatic masses
Grieser C, Steffen IG, Grajewski L, Stelter L, Streitparth F, Schnapauff D, Glanemann M, Langrehr J, Andreou A, Neuhaus P, Hamm B, Hänninen EL, Denecke T.
Distal pancreatectomy with splenectomy and en bloc resection of the celiac trunk for locally advanced cancer of the pancreatic body with infiltration of the celiac trunk
Andreou A, Glanemann M, Guckelberger O, Denecke T, Grieser C, Podrabsky P, Neuhaus P.
Modification of aminosilanized superparamagnetic nanoparticles: feasibility of multimodal detection using 3T MRI, small animal PET, and fluorescence imaging
L. Stelter, J. Pinkernelle, R. Michel, R. Schwartlander, N. Raschzok, M.H. Morgul, M. Koch, T. Denecke, H. Amthauer, J. Ruf, A. Jordan, B. Hamm, I.M. Sauer, U. Teichgraber
Aging of the liver graft and functional quality in the absence of recurrent disease: a 10 year histological follow-up
M. Schmeding, I.M. Sauer, K. Hartwig, T. Theruvath, J. Pratschke, R. Neuhaus, P. Neuhaus, U.P. Neumann
Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro
A. Diestel, S. Troeller, N. Billecke, I.M. Sauer, F. Berger, K.R.L. Schmitt
European Journal of Neuroscience, 2010; 31: 779-787
2009
Quantification of Cell Labelling with Micron-Sized Iron Oxide Particles Using Continuum Source Atomic Absorption Spectrometry
N. Raschzok, N. Billecke, N.N. Kammer, M.H. Morgul, M.K. Adonopoulou, I.M. Sauer, S. Florek, H. Becker-Ross, M.-D. Huang
Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its value as a serum marker in hepatocellular carcinomas
Riener MO, Stenner F, Liewen H, Soll C, Breitenstein S, Pestalozzi BC, Samaras P, Probst-Hensch N, Hellerbrand C, Müllhaupt B, Clavien PA, Bahra M, Neuhaus P, Wild P, Fritzsche F, Moch H, Jochum W, Kristiansen G.
Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its value as a serum marker in hepatocellular carcinomas
Riener MO, Stenner F, Liewen H, Soll C, Breitenstein S, Pestalozzi BC, Samaras P, Probst-Hensch N, Hellerbrand C, Müllhaupt B, Clavien PA, Bahra M, Neuhaus P, Wild P, Fritzsche F, Moch H, Jochum W, Kristiansen G.
Alpha-fetoprotein and serum golgi phosphoprotein 2 are equally discriminative in detecting early hepatocellular carcinomas
Riener MO, Stenner F, Liewen H, Hellerbrand C, Bahra M, Kristiansen G.
Nonresponse to pre-operative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases
Neumann UP, Thelen A, Röcken C, Seehofer D, Bahra M, Riess H, Jonas S, Schmeding M, Pratschke J, Bova R, Neuhaus P.
Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma
Riener MO, Pilarsky C, Gerhardt J, Grützmann R, Fritzsche FR, Bahra M, Weichert W, Kristiansen G.
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro in vivo
Lehmann A, Denkert C, Budczies J, Buckendahl AC, Darb-Esfahani S, Noske A, Müller BM, Bahra M, Neuhaus P, Dietel M, Kristiansen G, Weichert W.
Sonographically guided placement of intravenous catheters in minipigs
J. Pinkernelle, N. Raschzok, U. Teichgräber
Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes
T. Deurholt, N.P. van Til, A.A. Chhatta, L. ten Bloemendaal, R. Schwartlander, C. Payne, J.N. Plevris, I.M. Sauer, R.A. Chamuleau, R.P. Elferink, J. Seppen, R. Hoekstra
Aspergillus spondylodiscitis after multivisceral transplantation
U.A. Gerlach, S. Kohler, I.M. Sauer, D. Joerres, F. Kandziora, P. Neuhaus, J. Pratschke, A. Pascher
Tacrolimus and methylprednisolone prevent hypothermia induced endothelial dysfunction
A. Diestel, N. Billecke, J. Roessler, B. Schmitt, S. Troeller, R. Schwartlander, F. Berger, I.M. Sauer*, K.R.L. Schmitt*
Journal of Heart and Lung Transplantation, 2009, 28: 718-724 (IF: 3.514)
Successful treatment of invasive sphenoidal, pulmonary and intracerebral aspergillosis after multivisceral transplantation
S. Kohler, U. Gerlach, O. Guckelberger, I.M. Sauer, D. Jörres, P. Neuhaus, J. Pratschke, A. Pascher
2008
Imaging of Primary Human Hepatocytes Using Micron-Sized Iron Oxide Particles and Clinical Magnetic Resonance Tomography
N. Raschzok*, M.H. Morgul*, J. Pinkernelle, F.W.R. Vondran, N. Billecke, N.N. Kammer, G. Pless, M.K. Adonopoulou, C. Leist, L. Stelter, U. Teichgraber, R. Schwartlander, I.M. Sauer
Carcinoma of the distal and middle bile duct: surgical results, prognostic factors, and long-term follow-up
Bahra M, Jacob D, Langrehr JM, Neumann UP, Neuhaus P.
Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?
Glanemann M, Shi B, Liang F, Sun XG, Bahra M, Jacob D, Neumann U, Neuhaus P.
Tracking of primary human hepatocytes with clinical MRI – initial results with Tat-peptide modified superparamagnetic iron oxide particles
M.H. Morgul*, N.Raschzok*, R. Schwartlander, F.W.R. Vondran, R. Michel, L. Stelter, J. Pinkernelle, A. Jordan, U. Teichgraber, I.M. Sauer
Isolation of primary human hepatocytes after partial hepatectomy – Criteria for identification of the most promising liver specimen
F.W.R.Vondran, E. Katenz, R. Schwartlander, M.H. Morgul, N. Raschzok, X.B.Gong, X.D. Cheng, D. Kehr, I.M. Sauer
Graft versus host disease after liver transplantation - a single center experience and review of literature
S. Kohler, A. Pascher, G. Junge, I.M. Sauer, M. Nagy, C. Schönemann, M. Koch, U. Neumann, J. Pratschke, P. Neuhaus
Heterotopic ileal pancreas with lipoma and coexisting fibromatosis associated with a rare case of gastrointestinal bleeding. A case report and review of the literature.
P. Fikatas, I.M. Sauer, M. Mogl, C. Menenakos, A. Luegering, G. Schumacher, J. Langrehr, P. Neuhaus
Surgical treatment of a leiomyosarcoma of the inferior vena cava involving the hepatic and renal veins confluences: Technical aspects
A. Spinelli, G. Schumacher, C. Benckert, I.M. Sauer, M. Schmeding, M. Glanemann, U.P. Neumann, S. Jonas, P. Neuhaus
2007
Continuously microscopically observed and process controlled cell culture within the SlideReactor – proof of a new concept for cell characterization
R. Schwartlander, J. Schmid, B. Brandenburg, E. Katenz, F.W.R. Vondran, G. Pless, X. Cheng, A. Pascher, P. Neuhaus, I.M. Sauer
Somatostatin receptor subtype-2-deficient mice with diet-induced obestiy have hyperglycemia, non-fasting hyperglucagonemia and decreased hepatic glycogen deposition
V. Singh, C. Grotzinger, K.W. Nowak, S. Zacharias, E. Goncz, G. Pless, I.M. Sauer, I. Eichhorn, B. Pfeiffer-Guglielmi, B. Hamprecht, B. Wiedenmann, U. Plockinger, M.Z. Strowski
Surgical strategies and predictors of outcome for malignant neuroendocrine tumors of the pancreas
Bahra M, Jacob D, Pascher A, Plockinger U, Kristiansen G, Neuhaus P, Langrehr JM.
Combination therapy of poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide and gemcitabine shows strong antitumor activity in pancreatic cancer cells
Jacob DA, Bahra M, Langrehr JM, Boas-Knoop S, Stefaniak R, Davis J, Schumacher G, Lippert S, Neumann UP.
Antineoplastic activity of 2-methoxyestradiol in human pancreatic and gastric cancer cells with different multidrug-resistant phenotypes
Schumacher G, Hoffmann J, Cramer T, Spinelli A, Jacob D, Bahra M, Pratschke J, Pfitzmann R, Schmidt S, Lage H.
Artificial and Bioartificial Liver Support
G. Pless
Organogenesis 2007, 3: 20-24
Cryopreservation of primary human hepatocytes – the benefit of trehalose as an additional cryoprotective agent
E. Katenz, F.W.R. Vondran, R. Schwartlander, G. Pless, X. Gong, X. Cheng, P. Neuhaus, I. M. Sauer
Influence of basiliximab induction therapy on long term outcome after liver transplantation, a prospectively randomised trial
M. Schmeding, I.M. Sauer, A. Kiessling, J. Pratschke, R. Neuhaus, P. Neuhaus, U.P. Neumann
First in vitro comparison of two bioartificial liver support systems: MELS CellModule and AMC-BAL
P.P.C. Poyck, G. Pless, R. Hoekstra, S. Roth, A.C.W.A. van Wijk, R. Schwartlander, T.M. van Gulik, I.M. Sauer, R.A.F.M. Chamuleau
2006
Evaluation of primary human liver cells in bioreactor cultures for extracorporeal liver support on the basis of urea production
G. Pless, I. Steffen, K. Zeilinger, I.M. Sauer, E. Katenz, D.C. Kehr, S. Roth, T. Mieder, R. Schwartlander, Ch. Müller, B. Wegner, M. S. Hout, P. Neuhaus, J.C. Gerlach
Cell-free artificial liver support
I.M. Sauer, U. Baurmeister
Therapeutic Apheresis and Dialysis 2006, 10: 105-107 (IF: 1.177)
Jejunal loop drainage versus direct pancreatic duct drainage after pancreatic head resection
Jacob DA, Bahra M, Langrehr JM.
Peroxisome proliferator-activated receptor gamma is highly expressed in pancreatic cancer and is associated with shorter overall survival times
Kristiansen G, Jacob J, Buckendahl AC, Grützmann R, Alldinger I, Sipos B, Klöppel G, Bahra M, Langrehr JM, Neuhaus P, Dietel M, Pilarsky C.
Jejunal loop drainage versus direct pancreatic duct drainage after pancreatic head resection
Jacob DA, Bahra M, Langrehr JM.
Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature
A. Spinelli, G. Schumacher, A. Pascher, E. Lopez-Hanninen, H. Al-Abadi, C. Benckert, I.M. Sauer, J. Pratschke, U.P. Neumann, S. Jonas, J.M. Langrehr, P. Neuhaus
2005
Novel system for efficient gene transfer into primary human hepatocytes via cell permeable HBV virus-like particle
B. Brandenburg, L. Stockl, C. Gutzeit, M. Roos, J. Lupberger, R. Schwartlander, H. Gelderblom, I.M. Sauer, P.H. Hofschneider, E. Hildt
The SlideReactor - a simple hollow fiber based bioreactor suitable for light microscopy
I.M. Sauer, R. Schwartlander, J. Schmid, E. Efimova, F.W.R. Vondran, D. Kehr, G. Pless, A. Spinelli, B. Brandenburg, E. Hildt, and P. Neuhaus
Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth
Schumacher G, Oidtmann M, Rueggeberg A, Jacob D, Jonas S, Langrehr JM, Neuhaus R, Bahra M, Neuhaus P.
Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells
Jacob D, Schumacher G, Bahra M, Davis J, Zhu HB, Zhang LD, Teraishi F, Neuhaus P, Fang BL.
Overexpression of Polo-like kinase 1 is a common and early event in pancreatic cancer
Weichert W, Schmidt M, Jacob J, Gekeler V, Langrehr J, Neuhaus P, Bahra M, Denkert C, Dietel M, Kristiansen G.
Prospective randomized comparison between a new mattress technique and Cattell (duct-to-mucosa) pancreaticojejunostomy for pancreatic resection
Langrehr JM, Bahra M, Jacob D, Glanemann M, Neuhaus P.
Clinical results of intestinal and multivisceral transplantation at the Charité, Berlin
A. Pascher, J. Klupp, R.J. Schulz, S. Kohler, G. Junge, I.M. Sauer, W. Veltzke-Schlieker, A. Adler, O. Guckelberger, N.C. Nussler, A. Dignass, J.M. Langrehr, P. Neuhaus
In vitro evaluation of the transportability of viable primary human liver cells originating from discarded donor organs in bioreactors
I.M. Sauer, R. Schwartlander, O. van der Jagt, I. Steffen, E. Efimova, G. Pless, D.C. Kehr, D. Kardassis, J.H. Fruhauf, J.C. Gerlach, P. Neuhaus
Artificial Organs 2005, 29: 141-151 (IF: 1.946)
“Blogs” and “Wikis” are valuable software tools for communication within research groups
I.M. Sauer, D. Bialek, E. Efimova, R. Schwartlander, G. Pless, P. Neuhaus
The European artificial organ scene: present status
R. Vanholder, J. de Cañizo, I.M. Sauer, B Stegmayr
Bioartificial liver: current status
G. Pless, I.M. Sauer
2004
In vitro comparison of the Molecular Adsorbent Recirculation System (MARS) and Single Pass Albumin Dialysis (SPAD)
I.M. Sauer, M. Goetz, I. Steffen, G. Walter, D.C. Kehr, R. Schwartlander, Y.J. Hwang, A. Pascher, J.C. Gerlach, P. Neuhaus
Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter
Jacob D, Bahra M, Schumacher G, Neuhaus P, Fang B.
Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell lines
E.A. Efimova, M. Glanemann, L. Liu, G. Schumacher, U. Settmacher, S. Jonas, J.M. Langrehr, P. Neuhaus, A.K.Nussler
Bilirubin-adsorption in 23 critically ill patients with liver failure
R. Senf, R. Klingel, S. Kurz, S. Tullius, I.M. Sauer, U. Frei, R. Schindler
2003
The use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors – a morphological study
J.C. Gerlach, K. Mutig, I.M. Sauer, P. Schrade, E. Efimova, T. Mieder, G. Nauman, A. Grünwald, G. Pleß, A. Mas, S. Bachmann, P. Neuhaus, K. Zeilinger
Extracorporeal Liver Support based on Primary Human Liver Cells and Albumin Dialysis – Treatment of a Patient with Primary Graft Non-Function
I.M. Sauer, K. Zeilinger, G. Pless, D. Kardassis, T. Theruvath, A. Pascher, M. Goetz, P. Neuhaus, J. C. Gerlach
Porcine endogenous retroviruses (PERVs): No infection in patients treated with a bioreactor based on porcine liver cells
M. Irgang, I.M. Sauer, A. Karlas, K. Zeilinger, J.C. Gerlach, R. Kurth, P. Neuhaus, J. Denner
Clinical extracorporeal hybrid liver support – phase I study with primary porcine liver cells
I.M. Sauer, D. Kardassis, K. Zeillinger, A. Pascher, A. Gruenwald, G. Pless, M. Irgang, M. Kraemer, G. Puhl, J. Frank, A.R. Müller, Th. Steinmüller, J. Denner, P. Neuhaus, J. C. Gerlach
Successful infliximab treatment of steroid and OKT3 refractory acute cellular rejection in two patients after intestinal transplantation
A. Pascher, C. Radke, A. Dignass, R.J. Schulz, W. Veltzke-Schlieker, A. Adler, I.M. Sauer, K. Platz, J. Klupp, H.D. Volk, P. Neuhaus, A.R. Mueller
Late Graft Loss After Intestinal Transplantation in an Adult Patient as a Result of Necrotizing Enterocolitis
A. Pascher, C. Radke, A. Dignass, R. Schulz, I.M. Sauer, K. Platz, J. Klupp, P. Neuhaus, A. Mueller
Recovery of Preservation Injured Primary Human Hepatocytes and Nonparenchymal Cells to Tissue-Like Structures in Large-Scale Bioreactors for Liver Support: An Initial Transmission Electron Microscopy Study
J.C. Gerlach, K. Zeilinger, A. Grebe, G. Puhl, G. Pless, I.M. Sauer, A. Grunwald, N. Schnoy, C. Muller, P. Neuhaus
Einsatz biologischer Leberunterstützungssysteme bei der Therapie des Leberversagens – Modular Extracorporeal Liver Support (MELS)
T.P. Theruvath, I.M. Sauer, D. Kardassis, N. Obermayer, A. Pascher, M. Goetz, A.R. Mueller, Th. Steinmueller, P. Neuhaus, J.C. Gerlach
Verdauungskrankheiten 2003, 21: 32-40
2002
Concept for modular extracorporeal liver support for the treatment of acute hepatic failure
I.M. Sauer, P. Neuhaus, J.C. Gerlach
Extracorporeal liver support: Porcine or human cell based systems?
J.C. Gerlach, K. Zeilinger, I.M. Sauer, T. Mieder, G. Naumann, A. Grünwald, G. Pless, G. Holland, A. Mas, J. Vienken, P. Neuhaus
Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth
Schumacher G, Oidtmann M, Rosewicz S, Langrehr J, Jonas S, Mueller AR, Rueggeberg A, Neuhaus R, Bahra M, Jacob D, Gerlach H, Neuhaus P.
Primary human liver cells as source for modular extracorporeal liver support – a preliminary report
I.M. Sauer, K. Zeilinger, N. Obermayer, G. Pless, A. Pascher, T. Mieder, S. Roth, M. Goetz, D. Kardassis, A. Mas, P. Neuhaus, J.C. Gerlach
International Journal of Artificial Organs 2002, 25: 1001-1005 (IF: 1.192)
Analysis of allogeneic versus xenogeneic auxiliary organ perfusion in liver failure reveals superior efficacy of human livers
A. Pascher, I.M. Sauer, P. Neuhaus
International Journal of Artificial Organs 2002, 25: 1006-1012 (IF: 1.192)
Three-dimensional Co-culture of Primary Human Liver Cells in Bioreactors for In Vitro Drug Studies: Effects of the Initial Cell Quality on the Long-term Maintenance of Hepatocyte-specific Functions.
K. Zeilinger K, I.M. Sauer, G. Pless, C. Strobel, J. Rudzitis, A. Wang, A.K. Nussler, A. Grebe, L. Mao, S.H. Auth, J. Unger, P. Neuhaus, J.C. Gerlach
Modified surgical technique in clinical small bowel transplantation: donor and recipient management.
A. Mueller, A. Pascher, K. Platz, N. Nussler, R. Schulz,D. Horch,T. Melitz,I. M. Sauer, R. Eisele,U. Settmacher,A. Dignass,E. Lopez-Henninen,H. Weidemann,P. Neuhaus
Transplantation Proceedings 2002; 34: 2265 (IF: 0.478)
Living-Donation Liver Transplantation for Hepatocellular Carcinoma: Time to Drop the Limitations?
Th. Steinmüller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Müller, U.Settmacher, P. Neuhaus
Transplantation Proceedings 2002; 34: 2263-2264 (IF: 0.478)
A method to assess biochemical activity of liver cells during clinical application of extracorporeal liver support
A. Mundt, G. Puhl, A. Müller, I. Sauer, C. Müller, R. Richard, C. Fotopoulou, R. Doll, G. Gäblein, W. Höhn, R. Hofbauer, P. Neuhaus, J. Gerlach
Modular Extracorporeal Liver Support (MELS)
I.M. Sauer, J.C. Gerlach
Extracorporeal Liver Perfusion as Hepatic Assist in Acute Liver Failure - A Review of World Experience
A. Pascher, I.M. Sauer, C. Hammer, J.C. Gerlach, P. Neuhaus
[Right lobe living donor liver transplantation between adults]
T. Steinmuller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Muller, U. Settmacher , P. Neuhaus
Use of inferior mesenteric vein for venous anastomosis in clinical small bowel transplantation.
K.P. Platz, A. Pascher, R.J. Schulz, N.C. Nussler, I.M. Sauer, U. Settmacher, R. Eisele, A. Dignass, E. Lopez-Henninen, P. Neuhaus, A.R. Mueller
Transplantation Proceedings 2002, 34: 906-907 (IF: 0.478)
Monitoring of immunosuppression after clinical small bowel transplantation.
A. Pascher, I.M. Sauer, R.J. Schulz, K. Platz, T. Theruvath, A. Dignass, C. Radke, P. Neuhaus, A.R. Mueller
Transplantation Proceedings 2002, 34: 931-933 (IF: 0.478)
2001
Experimental evaluation of a cell module for hybrid liver support
J.C. Gerlach, M. Botsch, D. Kardassis, P. Lemmens, M. Schoen, J. Janke, G. Puhl, J. Unger, M. Kraemer, B. Busse, B. Boehmer, R. Belal, M. Ingenlath, M. Kosan, B. Kosan, J. Sueltmann, A. Patzold, S. Tietze, R. Roissant, C. Mueller, E. Moench, I.M. Sauer, P. Neuhaus
Development of a hybrid liver support system
I.M. Sauer, N. Obermayer, D. Kardassis, T. Theruvath, J.C. Gerlach
Modular Extracorporeal Liver Support (MELS) bei Leberversagen
D. Kardassis, T.P. Theruvath, I.M. Sauer, J.C. Gerlach, P. Neuhaus
Journal für Anästhesie und Intensivbehandlung 2001, 3: 97-99
Split liver and living donation liver transplantation: the Berlin experience.
I.M. Sauer, A. Pascher, Th. Steinmueller, U. Settmacher, A.R. Müller, W.O. Bechstein, P. Neuhaus
Transplantation Proceedings 2001; 33: 1459-1460 (IF: 0.568)
2000
Multiorgantransplantation
I.M. Sauer, A. Pascher, R. Pfitzmann, A.R. Mueller, P. Neuhaus
Chirurgische Praxis 2000, 57: 411-427
TAH Ovalis - Development and in vitro testing of a new electromechanical energy converter for a total artificial heart
I.M. Sauer, J. Frank, A.Spiegelberg, E.S. Bücherl
1999
An unusual case of early pancreas graft loss.
I.M. Sauer, A. Kahl, A.R. Müller, P. Neuhaus, W.O. Bechstein
Proposal of a new electro-mechanical heart: TAH Serpentina
I.M. Sauer, J. Frank, E.S. Bücherl
Adaptivität – die Zukunft digitaler Bildgebung? In: Adaptivität (Editors: M. Queisner, M. Bruhn, K. Friedrich, l. Kähny ) Hildesheim, Zürich, New York: Olms Weidmann
M. Queisner, M. Bruhn, K. Friedrich
Szenarien adaptiver Bildgebung In: Adaptivität (Editors: M. Queisner, M. Bruhn, K. Friedrich, l. Kähny ) Hildesheim, Zürich, New York: Olms Weidmann
M. Queisner, M. Bruhn, K. Friedrich, L. Kähny
Was sind adaptive Bilder? In: Adaptivität (Editors: M. Queisner, M. Bruhn, K. Friedrich, l. Kähny ) Hildesheim, Zürich, New York: Olms Weidmann
M. Queisner, M. Bruhn, K. Friedrich
Engineering an endocrine Neo-Pancreas. In: Decellularized Extracellular Matrix: Characterization, Fabrication and Applications (Editors: Tetsuji Yamaoka, Takashi Hoshiba)
E. Keshi, I.M. Sauer, K.H. Hillebrandt
Operieren im digitalen Raum – Mixed Reality in der Chirurgie. In: Die Zukunft der Medizin Disruptive Innovationen revolutionieren Medizin und Gesundheit (Editors: E. Böttinger, J. Zu Putlitz Jz)
I.M. Sauer, M. Queisner, M. Pogorzhelskiy, J. Pratschke
Liver Assist Systems for Bridging to Transplantation: Devices and Concepts. In: Critical Care for Potential Liver Transplant Candidates (Editors: (D. Bezinover and F. Saner)
N. Raschzok, K.H. Hillebrandt, I.M. Sauer
Preclinical swine models for monitoring of hepatocyte transplantation by MRI Hepatocyte Transplantation – Methods and Protocols (Editors: Stock, Christ)
N. Raschzok, U. Teichgräber, J. Pratschke, I.M. Sauer
Springer Verlag, 2017 (ISBN: 978-1-4939-6506-9)
Extracorporeal Liver Support, Liver-Cell Transplantation, and Bioengineered Substitutes. In: Textbook of Organ Transplantation (Editors: Kirk, Knechtle, Larsen, Pearson, Webber)
I.M. Sauer, N. Raschzok, P. Neuhaus
Wiley-Blackwell, 2014 (ISBN: 978-1-118-87014-3)
Extracorporeal liver support. In: Management of acute kidney problems (Editors: Ronco, Kellum, Jörres)
I.M. Sauer
Springer Verlag, 2009 (ISBN: 978-3-540-69413-7)
Akutes Nierenversagen bei Intensivpatienten: Extrakorporale Leberersatzverfahren (Editor: Jörres)
G. Pless, I.M. Sauer
Deutscher Ärzte Verlag, 2009 (ISBN 978-3-7691-0477-6)
Hybride Organe: Künstliche und zellbasierte Leberunterstützungssysteme. In: Chirurgische Forschung (Editors: Krukemeyer, Spiegel)
I.M. Sauer, P. Neuhaus
Georg Thieme Verlag, 2006: 366-378 (ISBN: 3-13-133661-7)
Modular Extracorporeal Liver Support. In: Artificial Liver Support (Editors: Henne-Bruns, Buttenschön, Fuchs, Lohse) Falk-Symposium, Vol. 145, 2005
I.M. Sauer
Springer Verlag, 2005: 53-60 (ISBN: 1-4020-3239-0)
Extrakorporale Leberunterstützungssysteme. In: Aktuelle Aspekte der Lebertransplantation (Editors: Neuhaus, Pfitzmann)
G. Puhl, I.M. Sauer
UniMed-Verlag, 2. Edition, 2005: 60-69 (ISBN 3-89599-774-9)
Liver Transplantation. In: Surgical treatment. Evidence-based and problem-oriented (Editor: Mannick)
I.M. Sauer, W.O. Bechstein, P. Neuhaus
Zuckschwerdt Verlag, München, Bern, Wien, New York: 298-305 (ISBN: 3-88603-714-2)
Bioartificial Organs III: Tissue Sourcing, Immunoisolation, and Clinical Trials (Editors: Hunkeler, Cherrington, Prokop, and Rajotte)
I.M. Sauer, N. Obermayer, D. Kardassis , T. Theruvath and J.C. Gerlach
Annals of the New York Academy of Sciences 2001, 944: 308-320 (ISBN: 1-57331-342-4)
Hepatozyten-Tissue Engineering und Bioreaktoren für hybride Leberunterstützungssysteme (Editor: Encke)
I.M. Sauer, J.C. Gerlach, P. Neuhaus
Deutsche Gesellschaft für Chirurgie – Kongressband 2000 : 764-769
Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay
Arnold A, Bahra M, Lenze D, Bradtmöller M, Guse K, Gehlhaar C, Bläker H, Heppner FL, Koch A.
Deutsche Gesellschaft für Chirurgie – Kongressband 2000 : 764-769
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