Selected Publications

Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the
Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.


Distinctive protein expression in elderly livers in a Sprague-Dawley rat model of normothermic ex vivo liver machine perfusion
M. Zimmer, K.H. Hillebrandt, N.M. Roschke, S. Lippert, O. Klein, G. Nebrich, J.M.G.V. Gassner, F. Strobl, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner

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Multinational Analysis of Marginal Liver Grafts Based on the Eurotransplant Extended Donor Criteria
S. Moosburner, M.S. Patel, B.K. Wang, J. Prasadh, R. Öllinger, G. Lurje, I.M. Sauer, P.A. Vagefi, J. Pratschke, N. Raschzok

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Comment on "Impact of Back-to-Base Normothermic Machine Perfusion on Complications and Costs: A Multi-Center, Real-World Risk-Matched Analysis"
K.A. Walter, M.S. Patel, I.M. Sauer, J. Pratschke, N. Raschzok, S. Moosburner

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Chemistry matters: A side-by-side comparison of two chemically distinct methacryloylated dECM bioresins for vat photopolymerization
A. Almalla, L. Elomaa, N. Fribiczer, T. Landes, P. Tang, Z. Mahfouz, B. Koksch, K.H. Hillebrandt, I.M. Sauer, D. Heinemann, S. Seiffert, M. Weinhart

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Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants
M.I. Ashraf, J. Mengwasser, A. Reutzel-Selke, D. Polenz, K. Führer, S. Lippert, P. Tang, E. Michaelis, R. Catar, J. Pratschke, Ch. Witzel, I.M. Sauer, S.G. Tullius, B. Kern

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Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome
N.N. Roschke, K.H. Hillebrandt, D. Polenz, O. Klein, J.M.G.V. Gassner, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner.

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Proteomic analysis of decellularized mice liver and kidney extracellular matrices
A.M. Diedrich, A. Daneshgar, P. Tang, O. Klein, A. Mohr, O.A. Onwuegbuchulam, S. von Rueden, K. Menck, A. Bleckmann, M.A. Juratli, F. Becker, I.M. Sauer, K.H. Hillebrandt, A. Pascher, B. Struecker

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Improved outcomes after hypothermic oxygenated machine perfusion in liver transplantation-Long-term follow-up of a multicenter randomized controlled trial.
Z. Czigany, D. Uluk, S. Pavicevic, I. Lurje, J. Froněk, Th. Keller, P. Strnad, D. Jiang, T. Gevers, D. Koliogiannis, M. Guba, R.H. Tolba, F.A. Meister, U.P. Neumann, M. Kocik, M. Kysela, I.M. Sauer, N. Raschzok, W. Schöning, I. Popescu, F. Tacke, J. Pratschke, G. Lurje

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Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels
A. Almalla, L. Elomaa, L. Bechtella, A. Daneshgar, P. Yavvari, Z. Mahfouz, P. Tang, B. Koksch, I. Sauer, K. Pagel, K.H. Hillebrandt, M. Weinhart

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Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering  
M.N. Andreas, A.K. Boehm, P. Tang, S. Moosburner, O. Klein, A. Daneshgar, J.M.G.V. Gaßner, N. Raschzok, D. Wulsten, J.-C. Rückert, S. Spuler, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

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Validation of risk scores for allograft failure after liver transplantation in Germany: a retrospective cohort analysis
S. Moosburner, L. Wiering, N. Roschke, A. Winter, Axel; M. Demir, J.M.G.V. Gaßner, M. Zimmer, P. Ritschl, B. Globke, G. Lurje, F. Tacke, W. Schöning, J. Pratschke, R. Öllinger, I.M. Sauer, N. Raschzok

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Augmenting Image-Guided Procedures through In Situ Visualization of 3D Ultrasound via a Head-Mounted Display
F. von Haxthausen, Ch. Rüger, M.M. Sieren, R. Kloeckner, F. Ernst

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Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models
V. Muth, J.M.G.V. Gassner, S. Moosburner, G. Lurje, J. Michelotto, F. Strobl, K. Knaub, C. Engelmann, F. Tacke, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok N

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Tissue engineering for the diaphragm and its various therapeutic possibilities – A Systematic Review
A.K. Boehm, K.H. Hillebrandt, T. Dziodzio, F. Krenzien, J. Neudecker, S. Spuler, J. Pratschke, I.M. Sauer, M.N. Andreas

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Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next-Generation Outcome Prediction in Transplantation Medicine
S. Moosburner, J.M.G.V. Gassner, J. Pratschke, I.M. Sauer, N. Raschzok

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Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
N. Krause, J. Mengwasser, E. Phithak, F. Beato, M. Appis, E.L. Milford, J. Pratschke J, I. Sauer, A. Kuehl, A. Vogel, M. Goodyear, L. Hammerich, F. Tacke, J.F. Haas, T. Müller, N. Utku N

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Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies
S. Gül-Klein, H. Hegermann, R. Röhle, M. Schmelzle, F. Tacke, W. Schöning, R. Öllinger, T. Dziodzio, P. Maier, J.M. Plewe, D. Horst, I.M. Sauer, J. Pratschke, N. Lachmann, D. Eurich

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Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study
K. Kamali, M. Schmelzle, C. Kamali, P. Brunnbauer, K. Splith, A. Leder, N. Berndt, K.H. Hillebrandt, N. Raschzok, L. Feldbrügge, M. Felsenstein, J. Gaßner, P. Ritschl, G. Lurje, W. Schöning, C. Benzing, J. Pratschke, F. Krenzien

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The Human Liver Matrisome – Proteomic Analysis of Native and Fibrotic Human Liver Extracellular Matrices for Organ Engineering Approaches
A. Daneshgar, O. Klein, G. Nebrich, M. Weinhart, P. Tang, A. Arnold, I. Ullah, J. Pohl, S. Moosburner, N. Raschzok, B. Strücker, M. Bahra, J. Pratschke, I.M. Sauer, K.H. Hillebrandt

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Title - Change Me

Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans
H. Napierala, K. Hillebrandt, N. Haep, P. Tang, M. Tintemann, J. Gassner, M. Noesser, H. Everwien, N. Seiffert, M. Kluge, E. Teegen, D. Polenz, S. Lippert, D. Geisel, A. Reutzel-Selke, N. Raschzok, A. Andreou, J. Pratschke, I.M. Sauer, B. Struecker

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Title - Change Me

Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions
B. Struecker, A. Butter, K. Hillebrandt, D. Polenz , A. Reutzel-Selke, P. Tang, S. Lippert, A. Leder, S. Rohn, D. Geisel, T. Denecke, K. Aliyev, K. Jöhrens, N. Raschzok, P. Neuhaus, J. Pratschke, I.M. Sauer

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Title - Change Me

CD44 and CXCL9 serum protein levels predict the risk of clinically significant allograft rejection after liver transplantation
N. Raschzok, A. Reutzel-Selke, R.B. Schmuck, M.H. Morgul, U. Gauger,K.A. Prabowo, L.-M. Tannus, A. Leder, B. Struecker, S. Boas-Knoop, M. Bartels, S. Jonas, Ch. Lojewski, G. Puhl, D. Seehofer, M. Bahra, A. Pascher, J. Pratschke, I.M. Sauer

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Title - Change Me

Porcine liver decellularization under oscillating pressure conditions – A technical refinement to improve the homogeneity of the decellularization process
B. Struecker, K. Hillebrandt, R. Voitl, A. Butter, R.B. Schmuck, A. Reutzel-Selke, D. Geisel, K. Joehrens, P.A. Pickerodt, N. Raschzok, G. Puhl, P. Neuhaus, J. Pratschke, I.M. Sauer

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Title - Change Me

Monitoring of liver cell transplantation in a preclinical swine model using Magnetic Resonance Imaging
N. Raschzok, U. Teichgräber, N. Billecke, A. Zielinski, K. Steinz, N.N. Kammer, M.H. Morgul, S. Schmeisser, M.K. Adonopoulou, L. Morawietz, B. Hiebl, R. Schwartlander, W. Rüdinger, B. Hamm, P. Neuhaus, I.M. Sauer

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Title - Change Me

Tacrolimus and methylprednisolone prevent hypothermia induced endothelial dysfunction
A. Diestel, N. Billecke, J. Roessler, B. Schmitt, S. Troeller, R. Schwartlander, F. Berger, I.M. Sauer*, K.R.L. Schmitt*

Journal of Heart and Lung Transplantation, 2009, 28: 718-724 (IF: 3.514)

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Title - Change Me

In vitro evaluation of the transportability of viable primary human liver cells originating from discarded donor organs in bioreactors
I.M. Sauer, R. Schwartlander, O. van der Jagt, I. Steffen, E. Efimova, G. Pless, D.C. Kehr, D. Kardassis, J.H. Fruhauf, J.C. Gerlach, P. Neuhaus

Artificial Organs 2005, 29: 141-151 (IF: 1.946)

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Title - Change Me

The use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors – a morphological study
J.C. Gerlach, K. Mutig, I.M. Sauer, P. Schrade, E. Efimova, T. Mieder, G. Nauman, A. Grünwald, G. Pleß, A. Mas, S. Bachmann, P. Neuhaus, K. Zeilinger

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Title - Change Me

Einsatz biologischer Leberunterstützungssysteme bei der Therapie des Leberversagens – Modular Extracorporeal Liver Support (MELS)
T.P. Theruvath, I.M. Sauer, D. Kardassis, N. Obermayer, A. Pascher, M. Goetz, A.R. Mueller, Th. Steinmueller, P. Neuhaus, J.C. Gerlach

Verdauungskrankheiten 2003, 21: 32-40

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Title - Change Me

Primary human liver cells as source for modular extracorporeal liver support – a preliminary report
I.M. Sauer, K. Zeilinger, N. Obermayer, G. Pless, A. Pascher, T. Mieder, S. Roth, M. Goetz, D. Kardassis, A. Mas, P. Neuhaus, J.C. Gerlach

International Journal of Artificial Organs 2002, 25: 1001-1005 (IF: 1.192)

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Title - Change Me

Analysis of allogeneic versus xenogeneic auxiliary organ perfusion in liver failure reveals superior efficacy of human livers
A. Pascher, I.M. Sauer, P. Neuhaus

International Journal of Artificial Organs 2002, 25: 1006-1012 (IF: 1.192)

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Title - Change Me

Modified surgical technique in clinical small bowel transplantation: donor and recipient management.
A. Mueller, A. Pascher, K. Platz, N. Nussler, R. Schulz,D. Horch,T. Melitz,I. M. Sauer, R. Eisele,U. Settmacher,A. Dignass,E. Lopez-Henninen,H. Weidemann,P. Neuhaus

Transplantation Proceedings 2002; 34: 2265 (IF: 0.478)

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Title - Change Me

Living-Donation Liver Transplantation for Hepatocellular Carcinoma: Time to Drop the Limitations?
Th. Steinmüller, A. Pascher, I.M. Sauer, T. Theruvath, A.R. Müller, U.Settmacher, P. Neuhaus

Transplantation Proceedings 2002; 34: 2263-2264 (IF: 0.478)

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Title - Change Me

Use of inferior mesenteric vein for venous anastomosis in clinical small bowel transplantation.
K.P. Platz, A. Pascher, R.J. Schulz, N.C. Nussler, I.M. Sauer, U. Settmacher, R. Eisele, A. Dignass, E. Lopez-Henninen, P. Neuhaus, A.R. Mueller

Transplantation Proceedings 2002, 34: 906-907 (IF: 0.478)

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Title - Change Me

Monitoring of immunosuppression after clinical small bowel transplantation.
A. Pascher, I.M. Sauer, R.J. Schulz, K. Platz, T. Theruvath, A. Dignass, C. Radke, P. Neuhaus, A.R. Mueller

Transplantation Proceedings 2002, 34: 931-933 (IF: 0.478)

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Title - Change Me

Modular Extracorporeal Liver Support (MELS) bei Leberversagen
D. Kardassis, T.P. Theruvath, I.M. Sauer, J.C. Gerlach, P. Neuhaus

Journal für Anästhesie und Intensivbehandlung 2001, 3: 97-99

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Title - Change Me

Split liver and living donation liver transplantation: the Berlin experience.
I.M. Sauer, A. Pascher, Th. Steinmueller, U. Settmacher, A.R. Müller, W.O. Bechstein, P. Neuhaus

Transplantation Proceedings 2001; 33: 1459-1460 (IF: 0.568)

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Title - Change Me

Preclinical swine models for monitoring of hepatocyte transplantation by MRI Hepatocyte Transplantation – Methods and Protocols (Editors: Stock, Christ)
N. Raschzok, U. Teichgräber, J. Pratschke, I.M. Sauer

Springer Verlag, 2017 (ISBN: 978-1-4939-6506-9)

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Title - Change Me

Extracorporeal Liver Support, Liver-Cell Transplantation, and Bioengineered Substitutes. In: Textbook of Organ Transplantation (Editors: Kirk, Knechtle, Larsen, Pearson, Webber)
I.M. Sauer, N. Raschzok, P. Neuhaus

Wiley-Blackwell, 2014 (ISBN: 978-1-118-87014-3)

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Title - Change Me

Extracorporeal liver support. In: Management of acute kidney problems (Editors: Ronco, Kellum, Jörres)
I.M. Sauer

Springer Verlag, 2009 (ISBN: 978-3-540-69413-7)

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Title - Change Me

Hybride Organe: Künstliche und zellbasierte Leberunterstützungssysteme. In: Chirurgische Forschung (Editors: Krukemeyer, Spiegel)
I.M. Sauer, P. Neuhaus

Georg Thieme Verlag, 2006: 366-378 (ISBN: 3-13-133661-7)

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Title - Change Me

Modular Extracorporeal Liver Support. In: Artificial Liver Support (Editors: Henne-Bruns, Buttenschön, Fuchs, Lohse) Falk-Symposium, Vol. 145, 2005
I.M. Sauer

Springer Verlag, 2005: 53-60 (ISBN: 1-4020-3239-0)

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Title - Change Me

Extrakorporale Leberunterstützungssysteme. In: Aktuelle Aspekte der Lebertransplantation (Editors: Neuhaus, Pfitzmann)
G. Puhl, I.M. Sauer

UniMed-Verlag, 2. Edition, 2005: 60-69 (ISBN 3-89599-774-9)

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Title - Change Me

Liver Transplantation. In: Surgical treatment. Evidence-based and problem-oriented (Editor: Mannick)
I.M. Sauer, W.O. Bechstein, P. Neuhaus

Zuckschwerdt Verlag, München, Bern, Wien, New York: 298-305 (ISBN: 3-88603-714-2)

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Title - Change Me

Bioartificial Organs III: Tissue Sourcing, Immunoisolation, and Clinical Trials (Editors: Hunkeler, Cherrington, Prokop, and Rajotte)
I.M. Sauer, N. Obermayer, D. Kardassis , T. Theruvath and J.C. Gerlach

Annals of the New York Academy of Sciences 2001, 944: 308-320 (ISBN: 1-57331-342-4)

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Title - Change Me

Hepatozyten-Tissue Engineering und Bioreaktoren für hybride Leberunterstützungssysteme (Editor: Encke)
I.M. Sauer, J.C. Gerlach, P. Neuhaus

Deutsche Gesellschaft für Chirurgie – Kongressband 2000 : 764-769

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