Impact of Hematocrit on Normothermic Machine Perfusion of Rat Liver Grafts and Viability Testing
J.R. Bornemann, L. Gilles, V. Appel, S. Moosburner, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
Selection is based on our experimental projects and involvement of our laboratories.
Regarding publications of the Dept. of Surgery, CCM|CVK, (in particular clinical projects) we would like to refer to Medline.
Impact of Hematocrit on Normothermic Machine Perfusion of Rat Liver Grafts and Viability Testing
J.R. Bornemann, L. Gilles, V. Appel, S. Moosburner, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
Isolation of functional human islets from pancreatectomy remnants: Determinants of yield and functionality
K.H. Hillebrandt, T. Lohmann, L. Haderer, S. Moosburner, M. Felsenstein, L.Ä. Böhne, A. Arnold, A. Reutzel-Selke, J. Pratschke, T. Malinka, I.M. Sauer, E. Keshi
Impact of Donor Age and Prolonged Warm Ischemia in Normothermic Machine Perfusion of Rat Livers
A.S. Pietsch, L. Boerger, L. Padoan, K.A. Walter, J.M. Gassner, O. Klein O, L.A. Böhne, A. Arnold, D. Horst, I. Iske, K.H. Hillebrandt, F. Krenzien, J. Pratschke, I.M. Sauer, N. Raschzok, S. Moosburner
Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection
A.M. Pfefferkorn, L. Jahn, P.T. Gauthier, V.A. Kulow, J. Roeles, N. Müller-Bötticher, L.M.S. Gerhardt, J. Leiz, S. Sarfraz, I. Plumbom, R. Greite, S. Lovric, J. Gamrekelashvili, F. Limbourg, J. Schmitz, J.M. Bräsen, I. Scheffner, I.M. Sauer, F. Aigner, J. Altmüller, T. Conrad, W. Gwinner, N. Ishaque, M. Fähling, K.M. Schmidt-Ott, P.F. Halloran, M.I. Ashraf, C. Hinze
Assessing age and cold ischemia effects on liver tissue viscoelastic properties: Implications for graft quality assessment with MRE during machine perfusion
L.M. Skrip, L. Boerger, K.A. Walter, A. Arnold, L.A. Böhne, E. Keshi, A.S. Pietsch, N. Raschzok, T.A. Auer, U. Fehrenbach, F. Krenzien, J. Pratschke, I.M. Sauer, J. Guo, J. Braun, H. Tzschätzsch, I. Sack, K.H. Hillebrandt, S. Moosburner
Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants
A.M. Pfefferkorn, R. Fritsche-Guenther, A. Kusch, H. Schwelberger, S. Liu, R. Klopfleisch, Y. Li, R. Catar, S. Liu, F. Aigner, J. Pratschke, I.M. Sauer, M.I. Ashraf
Lipocalin-2 Restores Soluble Guanylyl Cyclase-Dependent Dilation of the Afferent Arteriole After Renal Transplantation or Ex Vivo Hypoxia/Reoxygenation in Mice
L. Zhao, M. Xu, A.M. Pfefferkorn, C. Erdogan, H. Schwelberger, P. Wang, P.H. Khedkar, M. Eigen, F.B. Lichtenberger, R. Catar, E.Y Lai, F. Aigner, P.B. Persson, I.M. Sauer, A. Patzak, M.I. Ashraf
Comment on "Endotoxin, not DNA, determines the host response and tissue regeneration behavior of acellular biologic scaffolds"
E. Keshi, I.M. Sauer, K. Hillebrandt
Thrombogenicity assessment of perfusable tissue engineered constructs: a systematic review
L.M. Haderer, Y. Zhou, P. Tang, A. Daneshgar, B. Globke, F. Krenzien, A. Reutzel-Selke, M. Weinhart, J. Pratschke, I.M. Sauer, K.H. Hillebrandt, E. Keshi
Quality assessment by bile composition in normothermic machine perfusion of rat livers
V. Muth, F. Stobl, J. Michelotto, J.A. Kirwan, J. Marchand, N.N. Roschke, S. Moosburner, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
A new bicornuate model of rat uterus transplantation
D. Polenz, I.M. Sauer, F. Martin, A. Reutzel-Selke, M.I. Ashraf, A. Schirmeier, S. Lippert, K. Führer, J. Pratschke, S.G. Tullius, S. Moosburner.
Distinctive protein expression in elderly livers in a Sprague-Dawley rat model of normothermic ex vivo liver machine perfusion
M. Zimmer, K.H. Hillebrandt, N.M. Roschke, S. Lippert, O. Klein, G. Nebrich, J.M.G.V. Gassner, F. Strobl, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner
Multinational Analysis of Marginal Liver Grafts Based on the Eurotransplant Extended Donor Criteria
S. Moosburner, M.S. Patel, B.K. Wang, J. Prasadh, R. Öllinger, G. Lurje, I.M. Sauer, P.A. Vagefi, J. Pratschke, N. Raschzok
Comment on "Impact of Back-to-Base Normothermic Machine Perfusion on Complications and Costs: A Multi-Center, Real-World Risk-Matched Analysis"
K.A. Walter, M.S. Patel, I.M. Sauer, J. Pratschke, N. Raschzok, S. Moosburner
Chemistry matters: A side-by-side comparison of two chemically distinct methacryloylated dECM bioresins for vat photopolymerization
A. Almalla, L. Elomaa, N. Fribiczer, T. Landes, P. Tang, Z. Mahfouz, B. Koksch, K.H. Hillebrandt, I.M. Sauer, D. Heinemann, S. Seiffert, M. Weinhart
Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants
M.I. Ashraf, J. Mengwasser, A. Reutzel-Selke, D. Polenz, K. Führer, S. Lippert, P. Tang, E. Michaelis, R. Catar, J. Pratschke, Ch. Witzel, I.M. Sauer, S.G. Tullius, B. Kern
Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome
N.N. Roschke, K.H. Hillebrandt, D. Polenz, O. Klein, J.M.G.V. Gassner, J. Pratschke, F. Krenzien, I.M. Sauer, N. Raschzok, S. Moosburner.
Proteomic analysis of decellularized mice liver and kidney extracellular matrices
A.M. Diedrich, A. Daneshgar, P. Tang, O. Klein, A. Mohr, O.A. Onwuegbuchulam, S. von Rueden, K. Menck, A. Bleckmann, M.A. Juratli, F. Becker, I.M. Sauer, K.H. Hillebrandt, A. Pascher, B. Struecker
miRNA as potential biomarkers after liver transplantation: A systematic review
P.F. Koch, K. Ludwig, F. Krenzien, K.H. Hillebrandt, W. Schöning, J. Pratschke, N. Raschzok, I.M. Sauer, S. Moosburner
Improved outcomes after hypothermic oxygenated machine perfusion in liver transplantation-Long-term follow-up of a multicenter randomized controlled trial.
Z. Czigany, D. Uluk, S. Pavicevic, I. Lurje, J. Froněk, Th. Keller, P. Strnad, D. Jiang, T. Gevers, D. Koliogiannis, M. Guba, R.H. Tolba, F.A. Meister, U.P. Neumann, M. Kocik, M. Kysela, I.M. Sauer, N. Raschzok, W. Schöning, I. Popescu, F. Tacke, J. Pratschke, G. Lurje
Towards a 3D-printed perfusable islet embedding structure: technical notes and preliminary results
E. Keshi, P. Tang, T. Lam, S. Moosburner, L.M. Haderer, A. Reutzel-Selke, L. Kloke, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels
A. Almalla, L. Elomaa, L. Bechtella, A. Daneshgar, P. Yavvari, Z. Mahfouz, P. Tang, B. Koksch, I. Sauer, K. Pagel, K.H. Hillebrandt, M. Weinhart
Rise of tissue- and species-specific 3D bioprinting based on decellularized extracellular matrix-derived bioinks and bioresins
L. Elomaa, A. Almalla, E. Keshi, K.H. Hillebrandt, I.M. Sauer, M. Weinhart
Moderate LMWH anticoagulation improves success rate of hind limb allotransplantation in mice
B. Kern, M.-I. Ashraf, A. Reutzel-Selke, J. Mengwasser, D. Polenz, E. Michaelis, J. Pratschke, S.G. Tullius, Ch. Witzel, I.M. Sauer
Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering
M.N. Andreas, A.K. Boehm, P. Tang, S. Moosburner, O. Klein, A. Daneshgar, J.M.G.V. Gaßner, N. Raschzok, D. Wulsten, J.-C. Rückert, S. Spuler, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Advancing perfusion models: Dual-vessel ex vivo rat liver perfusion based on a clinical setup
F. Strobl, J. Michelotto, V. Muth, S. Moosburner, K. Knaub, M. Zimmer, M. Patel, J. Pratschke, I.M. Sauer, N. Raschzok, J.M.G.V. Gassner
How many liver transplantations could be recovered after implementation of donation after cardiac death in Germany?
S. Moosburner, I.M. Sauer, B. Weiß, J. Pratschke, N. Raschzok
Validation of risk scores for allograft failure after liver transplantation in Germany: a retrospective cohort analysis
S. Moosburner, L. Wiering, N. Roschke, A. Winter, Axel; M. Demir, J.M.G.V. Gaßner, M. Zimmer, P. Ritschl, B. Globke, G. Lurje, F. Tacke, W. Schöning, J. Pratschke, R. Öllinger, I.M. Sauer, N. Raschzok
Augmenting Image-Guided Procedures through In Situ Visualization of 3D Ultrasound via a Head-Mounted Display
F. von Haxthausen, Ch. Rüger, M.M. Sieren, R. Kloeckner, F. Ernst
Effect of pre-operative chemotherapy on the isolation outcome of primary human hepatocytes
M. Rissel, J. Pohl, S. Moosburner, J. Gaßner, R. Horner, K. Hillebrandt, D. Modest, J. Pratschke, I.M. Sauer, N. Raschzok
Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models
V. Muth, J.M.G.V. Gassner, S. Moosburner, G. Lurje, J. Michelotto, F. Strobl, K. Knaub, C. Engelmann, F. Tacke, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok N
Tissue engineering for the diaphragm and its various therapeutic possibilities – A Systematic Review
A.K. Boehm, K.H. Hillebrandt, T. Dziodzio, F. Krenzien, J. Neudecker, S. Spuler, J. Pratschke, I.M. Sauer, M.N. Andreas
Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next-Generation Outcome Prediction in Transplantation Medicine
S. Moosburner, J.M.G.V. Gassner, J. Pratschke, I.M. Sauer, N. Raschzok
Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
N. Krause, J. Mengwasser, E. Phithak, F. Beato, M. Appis, E.L. Milford, J. Pratschke J, I. Sauer, A. Kuehl, A. Vogel, M. Goodyear, L. Hammerich, F. Tacke, J.F. Haas, T. Müller, N. Utku N
Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies
S. Gül-Klein, H. Hegermann, R. Röhle, M. Schmelzle, F. Tacke, W. Schöning, R. Öllinger, T. Dziodzio, P. Maier, J.M. Plewe, D. Horst, I.M. Sauer, J. Pratschke, N. Lachmann, D. Eurich
Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study
K. Kamali, M. Schmelzle, C. Kamali, P. Brunnbauer, K. Splith, A. Leder, N. Berndt, K.H. Hillebrandt, N. Raschzok, L. Feldbrügge, M. Felsenstein, J. Gaßner, P. Ritschl, G. Lurje, W. Schöning, C. Benzing, J. Pratschke, F. Krenzien
Ex vivo machine perfusion: current applications and future directions in liver transplantation
J. Michelotto, J.M.G.V. Gassner, S. Moosburner, V. Muth, M.S. Patel, M. Selzner, J. Pratschke, I.M. Sauer, N. Raschzok
Extended liver resection in mice: state of the art and pitfalls – a systematic review
C. Kamali, K. Kamali, P. Brunnbauer, K. Splith, J. Pratschke, M. Schmelzle, F. Krenzien
Engineering an endothelialized, endocrine Neo-Pancreas: Evaluation of islet functionality in an ex vivo model
H. Everwien, E. Keshi, K.H. Hillebrandt, B. Ludwig, M. Weinhart, P. Tang , A.S. Beierle, H. Napierala, J.M. Gassner, N. Seiffert, S. Moosburner, D. Geisel, A. Reutzel-Selke, B. Strücker, J. Pratschke, N. Haep, I.M. Sauer
The Human Liver Matrisome – Proteomic Analysis of Native and Fibrotic Human Liver Extracellular Matrices for Organ Engineering Approaches
A. Daneshgar, O. Klein, G. Nebrich, M. Weinhart, P. Tang, A. Arnold, I. Ullah, J. Pohl, S. Moosburner, N. Raschzok, B. Strücker, M. Bahra, J. Pratschke, I.M. Sauer, K.H. Hillebrandt
Early Allograft Dysfunction Increases Hospital Associated Costs After Liver Transplantation-A Propensity Score-Matched Analysis
S. Moosburner, I.M. Sauer, F. Förster, T. Winklmann, J.M.G.V. Gassner, P.V. Ritschl, R. Öllinger, J. Pratschke, N. Raschzok
Declined Liver Grafts - Analysis of the German Donor Population from 2010 to 2018
S. Moosburner, N. Raschzok, C. Schleicher, D. Bösebeck, J.M.G.V. Gaßner, P.V. Ritschl, A. Rahmel, I.M. Sauer, J. Pratschke
Dual versus single vessel normothermic ex vivo perfusion of rat liver grafts using metamizole for vasodilatation
F. Claussen, J.M.G.V. Gassner, S. Moosburner, D. Wyrwal, M. Nösser, P. Tang, L. Wegener, J. Pohl, A. Reutzel-Selke, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
Development of GelMA/PCL and dECM/PCL resins for 3D printing of acellular in vitro tissue scaffolds by stereolithography
L. Elomaa, E. Keshi, I.M. Sauer, M. Weinhart
Increased Cell-Free DNA Plasma Concentration Following Liver Transplantation Is Linked to Portal Hepatitis and Inferior Survival
F. Krenzien, S. Katou, A. Papa, B. Sinn, C. Benzing, L. Feldbrügge, C. Kamali, P. Brunnbauer, K. Splith, R.R. Lorenz, P. Ritschl, L. Wiering, R. Öllinger, W. Schöning, J. Pratschke, M. Schmelzle
The Effects of MELD-Based Liver Allocation on Patient Survival and Waiting List Mortality in a Country with a Low Donation Rate
P.V. Ritschl, L. Wiering, T. Dziodzio, M. Jara, J. Kruppa, U. Schoeneberg, N. Raschzok, F. Butz, B. Globke, P. Seika, M. Maurer, M. Biebl, W. Schöning, M. Schmelzle, I.M. Sauer, F. Tacke, R. Öllinger, J. Pratschke
Magnetic resonance elastography quantification of the solid-to-fluid transition of liver tissue due to decellularization
H. Everwien, A. Ariza de Schellenberger, N. Haep, H. Tzschätzsch, J. Pratschke, I.M. Sauer, J. Braun, K.H. Hillebrandt, I. Sack
Hospitalization before liver transplantation predicts post-transplant patient survival - a propensity-score matched analysis
L. Wiering, R. Öllinger, J. Kruppa, U. Schoeneberg, T. Dziodzio, M. Jara, M. Biebl, R. Dargie, N. Raschzok, W. Schöning, D. Eurich, M. Schmelzle, I.M. Sauer, J. Pratschke, P.V. Ritschl
Development of a rat liver machine perfusion system for normothermic and subnormothermic conditions
M. Nösser, J.M.G.V. Gassner, S. Moosburner, D. Wyrwal, F. Claussen, K.H. Hillebrandt, R. Horner, P. Tang, A. Reutzel-Selke, D. Polenz, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
Hepatocyte Transplantation to the Liver via the Splenic Artery in a Juvenile Large Animal Model
J. Siefert, K.H. Hillebrandt, S. Moosburner, P. Podrabsky, D. Geisel, T. Denecke, J.K. Unger, B. Sawitzki, S. Gül-Klein, S. Lippert, P. Tang, A. Reutzel-Selke, M.H. Morgul, A.W. Reske, S. Kafert-Kasting, W. Rüdinger, J. Oetvoes, J. Pratschke, I.M. Sauer, N. Raschzok
Macrosteatosis is a huge problem in liver transplantation – however, not the only one we face
S. Moosburner, I.M. Sauer, J.M.G.V, Gassner, C. Schleicher, D. Bösebeck, A. Rahmel, J. Pratschke, N. Raschzok
Strategies based on organ decellularization and recellularization
K.H. Hillebrandt, H. Everwien, N. Haep, E. Keshi, J. Pratschke, I.M. Sauer
Diagnostic Biomarkers to Diagnose Acute Allograft Rejection After Liver Transplantation: Systematic Review and Meta-Analysis of Diagnostic Accuracy Studies
F. Krenzien, E. Keshi, K. Splith, S. Griesel, K. Kamali, I.M. Sauer, L. Feldbrügge, J. Pratschke, A. Leder, M. Schmelzle
Impact of Percoll purification on isolation of primary human hepatocytes
R. Horner, J.G.M.V. Gassner, M. Kluge, P. Tang, S. Lippert, K.H. Hillebrandt, S. Moosburner, A. Reutzel-Selke, J. Pratschke, I.M. Sauer, N. Raschzok
First Healthy Baby After Deceased Donor Uterus Transplantation: Birth to a New Era?
M.M. Maurer, I.M. Sauer, J. Pratschke, S.G. Tullius
Human Stem Cells Promote Liver Regeneration After Partial Hepatectomy in BALB/C Nude Mice
S. Wabitsch, C. Benzing, F. Krenzien, K. Splith, P.K. Haber, A. Arnold, M. Nösser, C. Kamali, F. Hermann, C. Günther, D. Hirsch, I.M. Sauer, J. Pratschke, M. Schmelzle
Mixed and Augmented Reality – Why Surgeons Should Care
M. Queisner, J. Pratschke, I.M. Sauer
Composite tissue allotransplantation: opportunities and challenges
J. Iske, Y. Nian, R. Maenosono, M. Maurer, I.M. Sauer, S.G. Tullius
High donor age for liver transplantation : Tackling organ scarcity in Germany
S. Moosburner, P.V. Ritschl, L. Wiering, J.M.G.V. Gassner, R. Öllinger , J. Pratschke, i.M. Sauer, N. Raschzok
Liver Assist Systems for Bridging to Transplantation: Devices and Concepts
N. Raschzok, K.H. Hillebrandt, I.M. Sauer
Improvement of normothermic ex vivo machine perfusion of rat liver grafts by dialysis and Kupffer Cell inhibition with glycine
J.M.G.V. Gassner, M. Nösser, S. Moosburner, R. Horner, P. Tang, L. Wegener, D. Wyrwal, F. Claussen, R. Arsenic, J. Pratschke, I.M. Sauer, N. Raschzok
Real world usability analysis of two augmented reality headsets in visceral surgery.
S. Moosburner, C. Remde, P. Tang, M. Queisner, N. Haep, J. Pratschke, I.M. Sauer
Prevalence of Steatosis Hepatis in the Eurotransplant Region: Impact on Graft Acceptance Rates
S. Moosburner, J.M.G.V. Gassner, M. Nösser, J. Pohl, D. Wyrwal, F. Claussen, P.V. Ritschl, D. Dragun, J. Pratschke, I.M. Sauer, N. Raschzok
Liver Transplantation and Liver Resection for Cirrhotic Patients with Hepatocellular Carcinoma: Comparison of Long-Term Survivals
F. Krenzien, M. Schmelzle, B. Struecker, N. Raschzok, C. Benzing, M. Jara, M. Bahra, R. Öllinger, I.M. Sauer, A. Pascher, J. Pratschke, A. Andreou
Living-Donor Liver Transplant: An Analysis of Postoperative Outcome and Health-Related Quality of Life in Liver Donors
C. Benzing, M. Schmelzle, R. Oellinger, K. Gruettner, A.K. Muehlisch, N. Raschzok, I.M. Sauer, M. Bahra, J. Pratschke, S. Guel-Klein
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