Einstein Visiting Fellow Prof. Stefan G. Tullius
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Prof. Dr. Stefan G. Tullius, Harvard Medical School, became Einstein BIH Visiting Fellow at the Charité, Department of Surgery. 

Vascular Composite Tissue Allotransplantation (VCA) has developed from a pioneering endevour to a clinical reality during the last 15 years. More than 150 extremity, face, knee, and most recently uterus and penis transplants have been performed during the last 15 years. VCA activities have been seen around the globe. Although feasibility of the procedure has been shown, it is still emerging and far from being a standard clinical procedure. 

The Charité has been an international leader in transplantation research for decades. However, neither VCA basic clinical research programs are currently offered in Berlin or Germany in a meaningful way.The involvement of Prof. Tullius as an Einstein BIH Visiting Fellow is expected to synergize and accelerate efforts igniting both a clinical research transplant program and a basic research group of excellence. The overall objective of our integrated basic and clinical research working group Vascular Composite Tissue Transplantation has three main goals:

To establish a basic Research group of Excellence: VCAs offer unique opportunities to study novel aspects of antigenicity, immune modulation and neo-vascularization. One important aspect that distinguishes VCA from solid organ transplants is their blood supply through a vascularized arterial in- and venous outflow in addition to sprouting new vessels at the large interface of VCA with recipient tissue.

To establish a clinical bio-repository as a pre-requisite for a clinical research VCA program.

To implement a clinical VCA research program (hand, abdominal wall, uterus) as a multi- disciplinary and translational effort.

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Presentations at DTG 2014
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Nathanael Raschzok presented his poster „Protein biomarkers for diagnosis and prediction of acute cellular rejection after liver transplantation“, Benjamin Strücker his work entitled „Oszillierende Druckschwankung verbessern signifikant die Ratten- und Schweineleber Dezellularisierung“ and Rosa Schmuck her posters „Risk of postoperative infections after LTX rises with MELD score“ and „Protein biomarkers in bile as a diagnostic tool after liver transplantation“.
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25th European Student´s Conference
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The ESC is one of the largest student-run biomedical conferences worldwide. It was established in 1989 as one of the first student conferences facilitating exchange between Western and Eastern Europe. Until today, it aims to foster international understanding within the young scientific community, and to promote high-quality science among young researchers in the biomedical field.

This year’s lecture series “Rethinking Medical Research – how do we achieve innovation?” will explore the dichotomy of medical advances by looking at both the opportunities and challenges that are presented to researchers and physicians. With topics ranging from open access policies, pharmaceutical innovations, and revolutionary health policies to advances in global health – we hope that this year’s topic will both challenge and inspire our participants!
The conference will take place from September 17th – 20th at the Virchow Klinikum Campus of the Charité Universitätsmedizin in Berlin, Germany.

More information here!
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Biologisierte Medizintechnik
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Die Berlin Partner für Wirtschaft und Technologie, Bereich Medizintechnik, die Charité - Universitätsmedizin Berlin und die IHK Berlin laden zum
28. Treffpunkt Medizintechnik „Biologisierte Medizintechnik“
am Donnerstag, 25. September 2014, 9 bis 17 Uhr
in der Charité – Universitätsmedizin Berlin, Campus Virchow-Klinikum
ein.
Mit dem „Treffpunkt Medizintechnik“ wird eine interdisziplinäre Dialogplattform für Klinik, Wissenschaft und Wirtschaft geboten.
Die Deadline für Vortragsmeldungen ist der 11. April 2014. Unter www.healthcapital.de/TP-Med finden Sie weitere Informationen und haben die Möglichkeit, sich auch online anzumelden.
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41st Annual Congress of the ESAO in Rome
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Prof. Celestino Pio Lombardi, Gemelli Polyclinics, Catholic University of the Sacred Heart in Rome, and Prof. Gerardo Catapano organize the 41st Annual Congress of the European Society for Artificial Organs (ESAO) in Rome, Italy.

The 41st ESAO Congress will be focused on “Patient happiness: the Holy Grail of organ substitution”, and will be held on September 17-20, 2014 at the Giovanni XXIII congress center located inside the Gemelli Polyclinics in Rome, Italy. The meeting is expected to attract aprox. 600 participants with both clinical and technical expertise from all over the world.
The objective of the Congress is to bring together scientists with different backgrounds working at the development, optimization and translation to the clinics of treatments of organ deficits based on the use of artificial, bioartificial, and cell-based organs or prostheses, and to discuss the importance of technical, psychological and ethical issues to the happiness of patients with serious tissue or organ deficits so as to re-define the design criteria of devices and treatments.
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12th Congress of the Cell Transplant Society
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The 12th Congress of the Cell Transplant Society tookplace in Milan, Italy, from July 7 to 11, 2013.
Nathanael Raschzok gave a presentation on "Loco-regional detection and stimulation of transplanted liver cells by particle-based miRNA depletion" and Martina Mogl on "isolation of adult hepatocytes and progenitor cells from explanted diseased human livers“.
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GASL Poster Prize
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Nathanael Raschzok's poster entitled "Serum protein biomarkers for acute rejection
in liver transplantation" was awarded with the GASL 2013 poster prize during the 29th Annual Meeting of the German Association for the Study of the Liver (GASL) in Hannover, Germany. Co-authors are Kukuh A. Prabowo, Anja Reutzel-Selke, Rosa B. Schmuck, Mehmet H. Morgul, Laura M. Tannus, Stephanie König, Sven Jonas, Peter Neuhaus, and Igor M. Sauer.


Although 20–40% of patients experience at least one episode of acute rejection (AR) after liver transplantation (LTx), diagnosis of AR is still mainly based on tissue analysis from liver biopsies. Biomarker routinely taken from blood samples would be a powerful non-invasive tool for monitoring of the liver graft status. The aim of this study was to investigate the diagnostic and prognostic value of serum protein biomarkers for acute rejection in LTx recipients. Serum samples from n=20 patients with AR and n=15 stable controls were analyzed. CXCL9 and CD31 were up-regulated in AR samples compared to controls at the time point of histologically proven rejection and at earlier time points prior rejection. Areas under the Receiver Operation Characteristics (ROC) curves were 0.6 and 0.7 at the day of rejection and 0.8 at POD1 for CXCL9 and CD31, respectively. IL-6 was increased prior and during rejection, while CD44 showed an opposite trend.
Serum protein biomarkers could be valuable for detection and prediction of AR after LTx. However, a larger number of patients, additional control groups, and prospective clinical trials will be necessary to proof the clinical utility of this diagnostic tool.

Moreover, Rosa Schmuck presented her data on "Bile: miRNA pattern and cell morphology as a diagnostic tool after liver transplantation" (co-authors: Nathanael Raschzok, Anja Reutzel-Selke, Steffen Lippert, Stephanie König, Kukuh A. Prabowo, Mehmet H. Morgul, Laura M. Tannus, Sven Jonas, Peter Neuhaus, and Igor M. Sauer) and Luisa Lisboa her work on "MicroRNA miR-352 in early liver regeneration: what role?" (co-authors: Nathanael Raschzok, Annekatrin Leder, Natalie Schlüter, Marc Jörres, Susanne Kolano, Antje Butter, Steffen Lippert, Wiebke Werner, Peter Neuhaus, and Igor M. Sauer).
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XXXX ESAO Congress in Glasgow
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The European Society for Artificial Organs (ESAO) invites you to the XXXX ESAO Congress of the society to be held in Glasgow (Scotland, UK), September 11th-14th 2013.The motto of the ESAO congress will be 'lab to patient - from concept to treatment.
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Presentations at EASO 2012 in Rostock, Germany
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This year members of the team gave the following presentations:

“Liver: Current regenerative strategies and future solutions for the liver" (N. Raschzok, oral presentation)
"Neohybrid liver graft - a novel concept of in vivo tissue-engineering" (S. Rohn, oral presentation)
"Micro RNAs in liver regeneration: the mysterious MIR-352" (L. Lisboa, oral presentation)
"Micron-sized iron oxide particles for detection and loco-regional stimulation of transplanted liver cells" (A. Leder, oral presentation)
"Prospective validation of cross organ serum protein biomarkers – Initial results with CXCL9 and CD44 for diagnosis of acute liver rejection" (K.A. Prabowo, poster presentation)
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TTS 2012 - Thank you!
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The Science Circuses are located at each end of the Exhibition Area. You will find the Mini-Theatres for the Mini-Oral Sessions here as well as the Poster Lounges and the Web Stations. Science Circus I includes Mini-Theatres 1 – 5; Science Circus II includes Mini-Theatres 6 – 10. In each Science Circus you will find Web Stations where you can access the web as well as the ePosters.
Via wireless headphones and dedicated channels for each mini-theater this is – to our knowledge – the first successful concept for mini-oral presentations!
Thanks to m-events and Interplan for the tremendous support!

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TTS 2012 | Over 500 presentations online!

The LOC would like to thank all participants for a tremendous 24th International Congress of The Transplantation Society in Berlin!
2268 abstracts were submitted and more than 4800 delegates from 94 countries attended the congress!
The Postgraduate Weekend offered 14 workshops with 45 speakers. Beside 29 Sunrise Symposia with 103 Speakers, 34 State of the Art Sessions with 138 speakers and five Plenary Sessions (16 speakers) we had 53 sessions with 465 oral presentations and 37 sessions with 287 mini oral presentations !
Furthermore, we would like to thank Astrid Enke, Lena Dochat and Stefanie Rensch (Interplan) and the technical experts at m-Events for their excellent work !
As Science and Medicine is nothing without vivid life we would like to thank Rotfront, Berlin Comedian Harmonists and the Capital Dance Orchestra for their memorable performances!

All the great photos by Jan Pauls.
The organ sculptures were made by Jan Pareike.

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ESAO 2012 - Final Program Online!

Prof. Dr. Gustav Steinhoff, congress president of the XXXIX. ESAO Congress, invites you to Rostock on September 26th – 29th, 2012. The venue of the ESAO 2012 congress is the Academy of Music and Theatre, which resides in an old monastery in the city centre.
The motto of the ESAO Congress 2012 will be “from replacement to regeneration – from science to clinic”. The current state of organ assist and organ support allows for a rapidly advancing clinical practice for several hundred thousand patients worldwide.
The scientific program committee did select 59 keynote lectures of renowned international experts, 131 selected oral presentations and 101 poster presentations from worldwide scientific contributors. Nine poster presentations were selected for short oral presentation. We provide a clear program structure by highlighting one special organ system each congress day: heart/cardiovascular (Chair: G. Steinhoff) , liver (Chair: S. Mitzner) and kidney (Chair: W. Ramlow). The program comprises 45 oral and 2 poster sessions with cardiovascular, dialysis, biomaterials and apheresis topics (www.esao2012.org). Above all the congress program integrates aspects of both basic science and clinical development with a clear focus on translation and clinical practice. We intend to host you on an excellent and exciting congress by inviting outstanding experts and by giving young and promising clinicians and scientists the opportunity to present their work. Especially for young scientists there will be one day for yESAO activities (Tuesday, Sept. 25, 2012). Industry symposia, a poster exhibition and an industrial exhibition will complete the congress program.

We are looking forward to seeing you in Rostock 2012.

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TTS 2012 | Presentations
We had 4 oral presentations and one poster presentation at TTS 2012..
Martina Mogl presented "Neohybrid Liver Graft - a Novel Concept of in Vivo Tissue-Engineering"
Rosa Schmuck presented our first results concerning "miRNA Pattern Within the Bile as a Diagnostic Tool after Liver Transplantation"
Nathanael Raschzok gave an oral presentation entitled "Silica-Based Micron-Sized Iron Oxide Particles for Detection and Loco-Regional Stimulation of Transplanted Liver Cells"
Haluk Morgül gave a talk on "MicroRNA as Biomarker for Diagnosis and Prediction of Recurrence of Human Hepatocellular Carcinoma after Liver Transplantation - Preliminary Results from a Multicenter Database"
Furthermore, the group presented a poster concerning "Prospective Validation of Serum Protein Biomarkers for Detection of Acute Liver Rejection – Initial Results with CXCL9 and CD44"
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XXXIX ESAO Congress in Rostock, Germany
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On behalf of the European Society for Artificial Organs (ESAO), Prof. Dr. med. Gustav Steinhoff invites you to the XXXIX. ESAO Congress to be held in Rostock (Germany), September 26th – 29th, 2012. Rostock is a prospering and easy-to-reach hanseatic city directly located at the Baltic Sea coast. The venue of the ESAO 2012 congress is the Academy of Music and Theatre, which resides in an old monastery in the city centre. Rostock is home to one of the oldest universities in the world: founded in 1419. The motto of the ESAO Congress 2012 will be “from replacement to regeneration – from science to clinic”. The meeting will provide a clear program structure by highlighting one special organ system each congress day: heart/cardiovascular, liver and kidney. Above all the congress program integrates aspects of both basic science and clinical development with a clear focus on translation and clinical practice. We intend to prepare an excellent and exciting congress by inviting outstanding experts and by giving young and promising clinicians and scientists the opportunity to present their work. Especially for young scientists there will be one day for yESAO activities. Industry symposia, a poster exhibition and an industrial exhibition will complete the congress program.
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TTS 2012 Abstract submission now open!
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Please join the mailing list and follow us via Twitter @TTS2012 for latest information concerning the 24th International Congress of The Transplantation Society to be held in Berlin, Germany from July 15th - 19th 2012 !
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TTS 2012: Follow us via Twitter!
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The 24th International Congress of The Transplantation Society to be held in Berlin, Germany from July 15th - 19th 2012 is designed for physicians, surgeons, scientists and organ procurement personnel, who are interested in clinical and research aspects of solid organ, cell and tissue transplantation. The program is developed to encourage the exchange of new scientific and clinical information, and support an interchange of opinions regarding care and management issues, as well as socioeconomic, ethical and regulatory issues relevant to transplantation.
In addition to the classical types of scientific sessions including plenary sessions, symposia, workshops and poster presentations, we will also offer new types of scientific sessions within the Forum Futurum.
The Forum Futurum is a forum integrated in the congress that will take place on three days. Each day is assigned to a topic and the forum is dedicated to cutting-edge science in our field. The topics are Regenerative Medicine, Imaging and Tailored Pharmacotherapy.
The Forum Futurum is designed to be a highly interactive communication space where companies can introduce their products and conversations about the latest research are stirred. In a futuristic environment the Forum Futurum contributes to an extraordinary TTS 2012 Exhibition experience and will provide exhibitors the opportunity to highlight new product information to physicians and health care professionals. Enhance the educational element of your company's noteworthy products and services with a presentation in the Forum Futurum. The Forum Futurum provides exhibitors with a unique and effective marketing opportunity to hold live promotional presentations or activities designed to raise awareness of featured services and products.
The Forum Futurum will make its debut in the TTS 2012 Exhibit Hall, featuring experts from companies and scientific groups providing state-of-the-art content-led information about new technologies, products and ideas. The Forum Futurum will be open July 16th – July 18th. Every day is dedicated to one emerging field in transplantation:
Monday, July 16th, 2012: One Day on Regenerative Medicine
Tuesday, July 17th, 2012: One Day on Imaging
Wednesday, July 18th, 2012: One Day on Tailored Pharmacotherapy
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Profiles of microRNA after rat partial hepatectomy
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The website of the 24th International Congress of The Transplantation Society is online! Please go to www.transplantation2012.org for more information.
Following the exceptionally successful meetings in Boston, Sydney and Vancouver, we would like to welcome you to a city which twenty years after reunification has evolved into one of the most important capitals of Europe. Once the capital of Prussia and leading cultural centre of the 1920s, today the new capital of Germany is characterized by its dazzling modernity and breathtaking architecture. Berlin is young, dynamic and bursting with joie de vivre. Few cities has been shaped to such an extent by history and undergone as much major transformation as Berlin. “Berlin is always in the process of becoming”, remarked historian Karl Scheffler. Even in the 21st century transplantation still is in a process of becoming, too. Therefore, the 24th International Congress of The Transplantation Society will promote the dialogue of experts from around the world. An attractive scientific program will be developed together with the Deutsche Transplantationsgesellschaft (DTG).
The 24th Congress is designed for physicians, surgeons, scientists and organ procurement personnel, who are interested in clinical and research aspects of solid organ, cell and tissue transplantation. The program is developed to encourage the exchange of new scientific and clinical information, and and support an interchange of opinions regarding care and management issues, as well as socioeconomic, ethical and regulatory issues relevant to transplantation.
In addition to the classical types of scientific sessions including plenary sessions, symposia, workshops and poster presentations, we will also offer new types of scientific sessions within the Forum Futurum focusing on Tailored Pharmacotherapy, Imaging and Regenerative Medicine. All of this is designed to develop a highly interactive forum to discuss cutting-edge science in our field.
We therefore cordially invite you and your colleagues together with your friends and family to come to Berlin. Your active participation in the scientific program will be the fundament for a successful event in 2012.
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