Prof. Dr. Stefan G. Tullius, Harvard Medical School, became Einstein BIH Visiting Fellow at the Charité, Department of Surgery.
Vascular Composite Tissue Allotransplantation (VCA) has developed from a pioneering endevour to a clinical reality during the last 15 years. More than 150 extremity, face, knee, and most recently uterus and penis transplants have been performed during the last 15 years. VCA activities have been seen around the globe. Although feasibility of the procedure has been shown, it is still emerging and far from being a standard clinical procedure.
The Charité has been an international leader in transplantation research for decades. However, neither VCA basic clinical research programs are currently offered in Berlin or Germany in a meaningful way.The involvement of Prof. Tullius as an Einstein BIH Visiting Fellow is expected to synergize and accelerate efforts igniting both a clinical research transplant program and a basic research group of excellence. The overall objective of our integrated basic and clinical research working group Vascular Composite Tissue Transplantation has three main goals:
To establish a basic Research group of Excellence: VCAs offer unique opportunities to study novel aspects of antigenicity, immune modulation and neo-vascularization. One important aspect that distinguishes VCA from solid organ transplants is their blood supply through a vascularized arterial in- and venous outflow in addition to sprouting new vessels at the large interface of VCA with recipient tissue.
To establish a clinical bio-repository as a pre-requisite for a clinical research VCA program.
To implement a clinical VCA research program (hand, abdominal wall, uterus) as a multi- disciplinary and translational effort.
Tags: VCA,Uterus Transplantation,Hand Transplantation,Composite Tissue Transplantation
Tags: Decellularization,Rezellularization,NeoPancreas,Islet Cells,Pancreas
Tags: Decellularization,Rezellularization,Liver,Transplantation
Tags: Cell Transplantation,MRI,Particles
More than 100 days of loops of learning and 3 days conquering more than 300 questions: 5 faces. Congratulations! We are all looking forward to having you back in the lab!
Tags: miRNA
Tags: Hepatocyte Isolation,Liver
Tags: Surgical Techniques
Tags: NeoHybrid Liver Graft,Cell Transplantation,Cell Culture,Cell Isolation,Liver Transplantation
Tags: miRNA,Liver Transplantation,Liver
Tags: Albumin Dialysis,Liver Support Therapy,Artificial Liver
Although we do hate Facebook, feel kind of robbed and dislike the music – We have to admit: 7,201,027 clicks (as of January 25th, 2016) are impressive…
Tags: Liver,Recellularization,Decellularization,Regeneration
Tags: Bile Ducts,Recellularization,Decellularization,Regeneration,Tissue Engineering
Tags: Cell Culture,Cell Isolation,Cell Transplantation,Liver
Karl Hillebrandt won this year's YPT Rising Stars Video Session Award. He presented the studies on „Optimized decellularization of rat livers by arterial and portal venous perfusion under oscillating pressure conditions“ during the 17th congress of the European Society for Organ Transplantation (ESOT) 2015 in Brüssel. Young Professionals in Transplantation (YPT) is a forum for junior professionals throughout Europe working in the field of transplantation.
Tags: Liver,Recellularization,Decellularization,Regeneration
Tags: Liver,Biomarkers,LTx
Tags: Decellularisation,Liver
Tags: miRNA,Tissue Engineering,Decellularization,Recellularization,Cell Transplantation
One of the figures of our paper „Porcine liver decellularization under oscillating pressure conditions – A technical refinement to improve the homogeneity of the decellularization process“ made it to the cover of the march issue of Tissue Engineering, Part C : Methods.
Congratulations to Dietrich Polenz, who made the corrosion cast of a decellularized pig liver matrix: red, hepatic artery; blue, portal vein; yellow, bile duct and gallbladder.
Tags: Particles
Tags: Decellulariztaion,Pancreas
Tags: INDY,Liver,Regeneration
Tags: DTG,Decellularization,miRNA
Tags: Recellularization,Decellularization,Liver,Liver Support Therapy
Tags: Decellularization,Liver
Tags: Call for papers
Tags: Decellularization
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